Kaballo Mohammed A, Brennan Darren D, El Bassiouni Mazen, Skehan Stephen J, Gupta Rajnish K
Mid-Western Cancer Centre, Mid-Western Regional Hospital, Dooradoyle, Limerick, Ireland.
J Med Case Rep. 2011 Aug 2;5:342. doi: 10.1186/1752-1947-5-342.
Intramedullary spinal cord metastasis is very rare. The majority are discovered incidentally during autopsy. Most symptomatic patients present with rapidly progressive neurological deficits and require immediate examination. Few patients demonstrate features of Brown-Séquard syndrome. Radiotherapy is the gold-standard of therapy for Intramedullary spinal cord metastasis. The overall prognosis is poor and the mortality rate is very high. We present what is, to the best of our knowledge, the first case of Intramedullary spinal cord metastasis of colorectal carcinoma presenting as Brown-Séquard syndrome.
We present the case of a 71-year-old Caucasian man with colonic adenocarcinoma who developed Intramedullary spinal cord metastasis and showed features of Brown-Séquard syndrome, which is an uncommon presentation of Intramedullary spinal cord metastasis.
This patient had an Intramedullary spinal cord metastasis, a rare form of metastatic disease, secondary to colonic carcinoma. The metastasis manifested clinically as Brown-Séquard syndrome, itself a very uncommon condition. This syndrome is rarely caused by intramedullary tumors. This unique case has particular interest in medicine, especially for the specialties of medical, surgical and radiation oncology. We hope that it will add more information to the literature about these entities.
脊髓髓内转移非常罕见。大多数是在尸检时偶然发现的。大多数有症状的患者表现为迅速进展的神经功能缺损,需要立即检查。很少有患者表现出布朗 - 塞卡尔综合征的特征。放射治疗是脊髓髓内转移的标准治疗方法。总体预后较差,死亡率很高。据我们所知,我们报告了首例以布朗 - 塞卡尔综合征为表现的结直肠癌脊髓髓内转移病例。
我们报告了一例71岁患有结肠腺癌的白种男性病例,该患者发生了脊髓髓内转移,并表现出布朗 - 塞卡尔综合征的特征,这是脊髓髓内转移的一种不常见表现。
该患者患有脊髓髓内转移,这是一种罕见的转移疾病形式,继发于结肠癌。该转移在临床上表现为布朗 - 塞卡尔综合征,其本身也是一种非常罕见的病症。这种综合征很少由髓内肿瘤引起。这个独特的病例在医学上具有特殊意义,特别是对于医学、外科和放射肿瘤学专业。我们希望它能为有关这些疾病的文献增添更多信息。