Yoshida Naoki, Hashimoto Yasunari, Shikota Mio, Ota Tetsuo
Department of Rehabilitation Medicine, Asahikawa Medical University Hospital , Asahikawa, Japan.
Department of Electrical and Electronic Engineering, Kitami Institute of Technology , Kitami, Japan.
Spinal Cord Ser Cases. 2016 Oct 27;2:16021. doi: 10.1038/scsandc.2016.21. eCollection 2016.
The aim of this study was to report the effects of brain-computer interface (BCI) training, a neurofeedback rehabilitation technique, on persistent neuropathic pain (NP) after cervical spinal cord injury (SCI).
We present the case of a 71-year-old woman with NP in her left upper extremity after SCI (C8). She underwent BCI training as outpatient rehabilitation for 4 months to enhance event-related desynchronization (ERD), which is triggered by the patient's motor intuition. Scalp electroencephalography was recorded to observe the ERD during every BCI training session. The patient's pain was evaluated with the McGill Pain Questionnaire (MPQ) and a visual analog scale (VAS). The MPQ was performed after every BCI training session, and the patient assessed the VAS score on her own, once every few days during the BCI training period.
After the BCI training started, the patient's ERD during the BCI training period increased significantly, from 15.6-30.3%. Moreover, her VAS score decreased gradually, from 8 to 5, after the BCI training started, although the MPQ did not change significantly.
BCI training has the potential to provide relief for patients with persistent NP via brain plasticity, and to improve their activities of daily living and quality of life.
本研究旨在报告脑机接口（BCI）训练（一种神经反馈康复技术）对颈脊髓损伤（SCI）后持续性神经性疼痛（NP）的影响。
我们报告了一名71岁女性的病例，她在SCI（C8）后出现左上肢NP。她作为门诊康复患者接受了4个月的BCI训练，以增强由患者运动直觉触发的事件相关去同步化（ERD）。在每次BCI训练期间记录头皮脑电图以观察ERD。用麦吉尔疼痛问卷（MPQ）和视觉模拟量表（VAS）评估患者的疼痛。每次BCI训练后进行MPQ评估，患者在BCI训练期间每隔几天自行评估VAS评分。
BCI训练开始后，患者在BCI训练期间的ERD显著增加，从1５.6%增至30.3%。此外，BCI训练开始后，她的VAS评分逐渐从8降至5，尽管MPQ没有显著变化。
BCI训练有可能通过脑可塑性为持续性NP患者减轻疼痛，并改善他们的日常生活活动能力和生活质量。
