Moriya Keiichi, Tamura Hideto, Nakamura Kyoko, Hosone Masaru, Inokuchi Koiti
Division of Hematology, Department of Medicine, Nippon Medical School 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan.
Shin Akasaka Clinic, Tokyo, Japan.
Leuk Res Rep. 2016 Dec 20;7:2-5. doi: 10.1016/j.lrr.2016.12.001. eCollection 2017.
Primary esophageal lymphoma is an extremely rare disease. We report a 76-year-old woman with esophageal lymphoma who achieved remission after (HP) eradication. Esophagogastroduodenoscopy (EGD) revealed a mass in the lower esophagus, and she was diagnosed with stage IE mucosa-associated lymphoid tissue (MALT) lymphoma. She rejected any anti-lymphoma treatment except for HP eradication. Follow-up EGD demonstrated the disappearance of the esophageal MALT lymphoma 2 months after HP eradication, and she remained in remission for more than 3 years. Our results demonstrate that HP eradication may be effective as initial therapy in primary esophageal MALT lymphoma patients with HP infection.
原发性食管淋巴瘤是一种极其罕见的疾病。我们报告了一名76岁患有食管淋巴瘤的女性,在根除幽门螺杆菌(HP)后病情缓解。食管胃十二指肠镜检查(EGD)显示食管下段有肿物,她被诊断为IE期黏膜相关淋巴组织(MALT)淋巴瘤。除了根除HP外,她拒绝任何抗淋巴瘤治疗。随访EGD显示,根除HP后2个月食管MALT淋巴瘤消失,并且她持续缓解超过3年。我们的结果表明,对于感染HP的原发性食管MALT淋巴瘤患者,根除HP可能作为初始治疗有效。