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一名原发性食管黏膜相关淋巴组织淋巴瘤患者在感染根除后未经抗淋巴瘤治疗即实现完全缓解。

A primary esophageal MALT lymphoma patient with infection achieved complete remission after eradication without anti-lymphoma treatment.

作者信息

Moriya Keiichi, Tamura Hideto, Nakamura Kyoko, Hosone Masaru, Inokuchi Koiti

机构信息

Division of Hematology, Department of Medicine, Nippon Medical School 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan.

Shin Akasaka Clinic, Tokyo, Japan.

出版信息

Leuk Res Rep. 2016 Dec 20;7:2-5. doi: 10.1016/j.lrr.2016.12.001. eCollection 2017.

Abstract

Primary esophageal lymphoma is an extremely rare disease. We report a 76-year-old woman with esophageal lymphoma who achieved remission after (HP) eradication. Esophagogastroduodenoscopy (EGD) revealed a mass in the lower esophagus, and she was diagnosed with stage IE mucosa-associated lymphoid tissue (MALT) lymphoma. She rejected any anti-lymphoma treatment except for HP eradication. Follow-up EGD demonstrated the disappearance of the esophageal MALT lymphoma 2 months after HP eradication, and she remained in remission for more than 3 years. Our results demonstrate that HP eradication may be effective as initial therapy in primary esophageal MALT lymphoma patients with HP infection.

摘要

原发性食管淋巴瘤是一种极其罕见的疾病。我们报告了一名76岁患有食管淋巴瘤的女性,在根除幽门螺杆菌(HP)后病情缓解。食管胃十二指肠镜检查(EGD)显示食管下段有肿物,她被诊断为IE期黏膜相关淋巴组织(MALT)淋巴瘤。除了根除HP外,她拒绝任何抗淋巴瘤治疗。随访EGD显示,根除HP后2个月食管MALT淋巴瘤消失,并且她持续缓解超过3年。我们的结果表明,对于感染HP的原发性食管MALT淋巴瘤患者,根除HP可能作为初始治疗有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0afd/5196236/739fafac917b/gr1.jpg

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