Golioto M, McGrath K
Division of Gastroenterology, Duke University Medical Center, Durham, North Carolina, USA.
Am J Med Sci. 2001 Mar;321(3):203-5. doi: 10.1097/00000441-200103000-00010.
Adenocarcinoma and squamous cell carcinoma account for the vast majority of esophageal malignancies. Other malignancies that can involve the esophagus include melanoma, sarcoma, and lymphoma. Gastrointestinal involvement with lymphoma has a variable incidence, as reported in the literature. However, primary involvement, as defined by Dawson, is extremely rare. Lymphoma has been linked to immunosuppressive conditions (such as AIDS), medications, and transplantation. We present what we believe to be the first case of primary esophageal lymphoma in a patient on long-term immunosuppression with azathioprine who was also infected with the hepatitis C virus (HCV). HCV has been postulated to have a relationship with B cell lymphomas.
腺癌和鳞状细胞癌占食管恶性肿瘤的绝大多数。其他可累及食管的恶性肿瘤包括黑色素瘤、肉瘤和淋巴瘤。如文献报道，胃肠道淋巴瘤的发病率各不相同。然而，按照道森的定义，原发性累及极为罕见。淋巴瘤与免疫抑制状况（如艾滋病）、药物及移植有关。我们报告了我们认为是首例长期使用硫唑嘌呤免疫抑制且感染丙型肝炎病毒（HCV）患者的原发性食管淋巴瘤病例。据推测，HCV与B细胞淋巴瘤有关。
