Khan Suliman, Ullah Muhammad Wajid, Siddique Rabeea, Nabi Ghulam, Manan Sehrish, Yousaf Muhammad, Hou Hongwei
The Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, China.
Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China.
Int J Genomics. 2016;2016:2405954. doi: 10.1155/2016/2405954. Epub 2016 Dec 8.
In the past century, the recombinant DNA technology was just an imagination that desirable characteristics can be improved in the living bodies by controlling the expressions of target genes. However, in recent era, this field has demonstrated unique impacts in bringing advancement in human life. By virtue of this technology, crucial proteins required for health problems and dietary purposes can be produced safely, affordably, and sufficiently. This technology has multidisciplinary applications and potential to deal with important aspects of life, for instance, improving health, enhancing food resources, and resistance to divergent adverse environmental effects. Particularly in agriculture, the genetically modified plants have augmented resistance to harmful agents, enhanced product yield, and shown increased adaptability for better survival. Moreover, recombinant pharmaceuticals are now being used confidently and rapidly attaining commercial approvals. Techniques of recombinant DNA technology, gene therapy, and genetic modifications are also widely used for the purpose of bioremediation and treating serious diseases. Due to tremendous advancement and broad range of application in the field of recombinant DNA technology, this review article mainly focuses on its importance and the possible applications in daily life.
在过去的一个世纪里,重组DNA技术还只是一种设想,即通过控制目标基因的表达来改善生物体的理想特性。然而,在当今时代,这一领域已在推动人类生活进步方面展现出独特影响。借助这项技术,可以安全、经济且充足地生产出健康问题和饮食目的所需的关键蛋白质。该技术具有多学科应用,并有潜力应对生活中的重要方面,例如改善健康、增加食物资源以及抵御各种不利环境影响。特别是在农业领域,转基因植物增强了对有害生物的抗性,提高了产量,并表现出更强的适应性以实现更好的生存。此外,重组药物如今正被放心使用,并迅速获得商业批准。重组DNA技术、基因治疗和基因修饰技术也广泛用于生物修复和治疗严重疾病。由于重组DNA技术领域取得了巨大进展且应用广泛,本文主要关注其重要性以及在日常生活中的可能应用。