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Implications of MRGPRX2 in human and experimental cardiometabolic diseases.

作者信息

Azimi Ehsan, Lerner Ethan A

机构信息

Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

出版信息

Nat Rev Cardiol. 2017 Feb;14(2):124. doi: 10.1038/nrcardio.2016.212. Epub 2017 Jan 5.

DOI:10.1038/nrcardio.2016.212
PMID:28054574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5523950/
Abstract
摘要

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本文引用的文献

1
Dual action of neurokinin-1 antagonists on Mas-related GPCRs.神经激肽-1 拮抗剂对 Mas 相关 GPCR 的双重作用。
JCI Insight. 2016 Oct 6;1(16):e89362. doi: 10.1172/jci.insight.89362.
2
Mast cells in human and experimental cardiometabolic diseases.人类和实验性心血管代谢疾病中的肥大细胞。
Nat Rev Cardiol. 2015 Nov;12(11):643-58. doi: 10.1038/nrcardio.2015.117. Epub 2015 Aug 11.
3
Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.重新定义蛋白酶激活受体的概念:组织蛋白酶S通过激活Mrgprs引发瘙痒。
Nat Commun. 2015 Jul 28;6:7864. doi: 10.1038/ncomms8864.
4
Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions.鉴定对伪过敏性药物反应至关重要的肥大细胞特异性受体。
Nature. 2015 Mar 12;519(7542):237-41. doi: 10.1038/nature14022. Epub 2014 Dec 17.
5
Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria.肥大细胞相关基因 X2 在重症慢性荨麻疹患者皮肤中的表达上调。
J Allergy Clin Immunol. 2014 Sep;134(3):622-633.e9. doi: 10.1016/j.jaci.2014.05.004. Epub 2014 Jun 19.
6
Tachykinin receptors antagonism for asthma: a systematic review.速激肽受体拮抗剂治疗哮喘:系统评价。
BMC Pulm Med. 2011 Aug 2;11:41. doi: 10.1186/1471-2466-11-41.
7
The neuropeptide substance P mediates adventitial mast cell activation and induces intraplaque hemorrhage in advanced atherosclerosis.神经肽 P 介导动脉外膜 mast 细胞激活,并在晚期动脉粥样硬化中诱导斑块内出血。
Circ Res. 2010 Jan 8;106(1):89-92. doi: 10.1161/CIRCRESAHA.109.204875. Epub 2009 Nov 19.
8
Substance P receptor antagonists in the therapy of migraine.
Expert Opin Investig Drugs. 2001 Apr;10(4):673-8. doi: 10.1517/13543784.10.4.673.