Shetty H G, O'Sullivan M M, Amos N, Williams B D
Department of Rheumatology, University Hospital of Wales, Cardiff, UK.
Clin Rheumatol. 1989 Sep;8(3):381-5. doi: 10.1007/BF02030352.
We describe a 63-year-old female who developed the CREST syndrome within two years. Even though she was anticentromere antibody positive, her illness followed a very aggressive course and was associated with severe polyarthritis, renal impairment, hypocomplementaemia and mixed cryoglobulinaemia.
我们描述了一位63岁的女性,她在两年内患上了CREST综合征。尽管她抗着丝点抗体呈阳性,但她的病情发展非常迅速,伴有严重的多关节炎、肾功能损害、补体血症和混合性冷球蛋白血症。