Iovino Michele, Giagulli Vito Angelo, Licchelli Brunella, Iovino Emanuela, Guastamacchia Edoardo, Triggiani Vincenzo
Interdisciplinary Department of Medicine-University of Bari "Aldo Moro", Bari, Italy.
Endocr Metab Immune Disord Drug Targets. 2016;16(4):276-287. doi: 10.2174/1871530317666170104124229.
Magnocellular neurosecretory neurons of the hypothalamic supraoptic (SON) and paraventricular (PVN) nuclei synthesize vasopressin and oxytocin in response to signals generated by osmoreceptors and baroreceptors and, respectively, by receptors of the nipples and cervix.
We analyzed the literature identifying relevant articles dealing with synaptic inputs of neural afferent pathways to Vasopressin-and Oxytocin-secreting neurons of SON and PVN.
This article focuses on the multisynaptic pathways involved in the regulation of Vasopressin and Oxytocin secretion.
An updated topographic description of the afferent pathways involved in the regulation of VPergic and OTergic neurons and their synaptic inputs inducing the stimulus-secretion-coupling has been depicted.
下丘脑视上核（SON）和室旁核（PVN）的大细胞神经分泌神经元分别响应渗透压感受器和压力感受器产生的信号，以及乳头和子宫颈的感受器产生的信号，合成血管加压素和催产素。
我们分析了相关文献，确定了涉及神经传入通路至SON和PVN中血管加压素和催产素分泌神经元的突触输入的相关文章。
本文重点关注参与血管加压素和催产素分泌调节的多突触通路。
已描绘了参与调节血管加压素能和催产素能神经元及其诱导刺激-分泌偶联的突触输入的传入通路的最新地形图。
