Biology Department, Science Faculty, Firat University, Elazig. Turkey.
Nutrition Department, Veterinary Faculty, Firat University, Elazig. Turkey.
Curr Vasc Pharmacol. 2017;15(4):327-338. doi: 10.2174/1570161115666170105122616.
There has been an increasing interest in the usage of natural products for the prevention and treatment of chronic diseases such as cardiovascular disease (CVD). Regular consumption of fruits, vegetables and whole grains has been shown to be negatively correlated with the risk of CVDs. These foods provide a diversity of nutrients and different bioactive compounds including phytochemicals, vitamins, minerals and fibers which play critical roles in the sustainability of optimal cardiovascular health. Plant-based foods or a nutritional cure are gradually being integrated into medical practice for CVD management partly due to the supporting experimental studies, clinical trials and epidemiological studies. These products have anti-oxidant, anti-inflammatory, hypoglycemic, hypolipidemic, hypotensive, anti-atherosclerotic, anti-thrombotic and hypocholesterolemic effects, depending on the dosage in cell and tissue cultures, animal models as well as in humans. The present review considers some novel ideas on some major phytochemicals which have been suggested to have protective and therapeutic potential in CVD. The data presented in this work have been compiled from studies that have mostly been carried out in recent years.
人们越来越关注利用天然产物来预防和治疗心血管疾病（CVD）等慢性病。经常食用水果、蔬菜和全谷物与 CVD 风险呈负相关。这些食物提供了多种营养物质和不同的生物活性化合物，包括植物化学物质、维生素、矿物质和纤维，它们在维持最佳心血管健康方面起着至关重要的作用。植物性食物或营养疗法正逐渐被纳入 CVD 管理的医疗实践中，部分原因是有实验研究、临床试验和流行病学研究的支持。这些产品具有抗氧化、抗炎、降血糖、降血脂、降血压、抗动脉粥样硬化、抗血栓形成和降胆固醇作用，具体取决于细胞和组织培养、动物模型以及人类中的剂量。本综述考虑了一些关于主要植物化学物质的新观点，这些物质被认为具有 CVD 的保护和治疗潜力。本工作中呈现的数据主要是近年来开展的研究中收集的。
