Cavelier C, Foussereau J, Gille P, Zissu D
Institut National de Recherche et de Sécurité, Vandoeuvre, France.
Contact Dermatitis. 1989 Aug;21(2):72-8. doi: 10.1111/j.1600-0536.1989.tb04700.x.
The aim of this study was to evaluate, in animals and humans sensitive to nickel or cobalt, the tolerance to manufactured metal samples of nickel and cobalt of a defined metallographic structure, plated or not with a layer of chrome or copper/chrome of a determined thickness. Under the defined experimental conditions, a guinea pig sensitized to one metal (nickel or cobalt) was intolerant to both metals (nickel and cobalt). A plating of chrome or copper/chrome did not act as a protection. In the human, it was not the same: the tolerance to metal samples was determined by the specific sensitivity. A plating of chrome or copper/chrome did not act as protection.
