Cornelisse Vincent J, Sherman Christopher J, Hocking Jane S, Williams Henrietta, Zhang Lei, Chen Marcus Y, Bradshaw Catriona S, Bellhouse Clare, Fairley Christopher K, Chow Eric P F
Melbourne Sexual Health Centre, Alfred Health, 580 Swanston St, Carlton, Melbourne, VIC, 3052, Australia.
Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
BMC Infect Dis. 2017 Jan 5;17(1):22. doi: 10.1186/s12879-016-2141-7.
Our study aimed to describe the concordance of chlamydia infections of the rectum and urethra in men who have sex with men (MSM) and their male partners.
This was a cross-sectional study of chlamydia in MSM and their male sexual partners both attending Melbourne Sexual Health Centre (MSHC), Australia, between February 2011 and March 2015. We excluded partnerships where testing for chlamydia at both the rectum and urethra were not undertaken.
Our study included 473 partnerships (946 men). 30 men had urethral chlamydia, of whom 14 (47%, 95% CI 28 to 66) had a partner with rectal chlamydia. 46 men had rectal chlamydia, of whom 14 (30%, 95% CI 18 to 46) had a partner with urethral chlamydia. The proportion of men with rectal chlamydia when their partner had urethral chlamydia was significantly higher than the proportion of men with urethral chlamydia when their partner had rectal chlamydia (McNemar's p = 0.02).
This is the first study of chlamydia concordance in male sexual partnerships and suggests that transmission of chlamydia between the urethra and rectum may be less efficient than has been reported for transmission between the urethra and cervix in heterosexual couples. It also suggests that transmission from the urethra to the rectum may be more efficient than in the opposite direction.
我们的研究旨在描述男男性行为者（MSM）及其男性伴侣中直肠和尿道衣原体感染的一致性。
这是一项对2011年2月至2015年3月期间在澳大利亚墨尔本性健康中心（MSHC）就诊的男男性行为者及其男性性伴侣进行的衣原体横断面研究。我们排除了未对直肠和尿道进行衣原体检测的伴侣关系。
我们的研究纳入了473对伴侣关系（946名男性）。30名男性患有尿道衣原体感染，其中14名（47%，95%可信区间28%至66%）的伴侣患有直肠衣原体感染。46名男性患有直肠衣原体感染，其中14名（30%，95%可信区间18%至46%）的伴侣患有尿道衣原体感染。伴侣患有尿道衣原体感染时，患有直肠衣原体感染的男性比例显著高于伴侣患有直肠衣原体感染时患有尿道衣原体感染的男性比例（麦克尼马尔检验p = 0.02）。
这是第一项关于男性性伴侣中衣原体一致性的研究，表明衣原体在尿道和直肠之间的传播效率可能低于异性恋伴侣中尿道和宫颈之间传播的报道效率。这也表明从尿道到直肠的传播可能比相反方向更有效。
