在细针穿刺活检中被判定为良性的大甲状腺结节更有可能暗藏癌症吗？
Are large thyroid nodules classified as benign on fine needle aspiration more likely to harbor cancer?
作者信息
Shi Helen, Bobanga Iulianna, McHenry Christopher R
机构信息
Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA; Department of Surgery, University Hospitals Case Medical Center, Cleveland, OH, 44106, USA.
出版信息
Am J Surg. 2017 Mar;213(3):464-466. doi: 10.1016/j.amjsurg.2016.10.028. Epub 2016 Dec 28.
INTRODUCTION
Our aim was to investigate whether benign thyroid nodules ≥ 4 cm have a higher malignancy rate.
METHODS
A retrospective review of patients with a nodule and a benign FNAB who underwent thyroidectomy was completed. Patients were divided into two groups; nodule size: < 4 cm or ≥4 cm, and clinical factors, nodule size and rates of malignancy were compared.
RESULTS
337 patients underwent thyroidectomy: 99 had nodules <4 cm (2.8 ± 0.58 cm) and 238 had nodules ≥ 4 cm (5.9 ± 1.97 cm). Seven (2.1%) patients had cancer, 2 (2.0%) with a nodule < 4 cm and 5 (2.1%) with a nodule ≥ 4 cm (p = 0.962). There was no difference in clinical factors between groups (p > 0.05).
CONCLUSION
There is no difference in rates of malignancy for nodules < 4 cm or ≥ 4 cm. Thus, thyroidectomy should not be recommended based solely on nodule size.
引言
我们的目的是研究直径≥4 cm的甲状腺良性结节是否具有更高的恶性率。
方法
对接受甲状腺切除术的有结节且细针穿刺活检（FNAB）结果为良性的患者进行回顾性研究。患者分为两组；结节大小：<4 cm或≥4 cm，并比较临床因素、结节大小和恶性率。
结果
337例患者接受了甲状腺切除术：99例患者的结节<4 cm（2.8±0.58 cm），238例患者的结节≥4 cm（5.9±1.97 cm）。7例（2.1%）患者患有癌症，2例（2.0%）结节<4 cm，5例（2.1%）结节≥4 cm（p = 0.962）。两组之间的临床因素无差异（p>0.05）。
结论
直径<4 cm或≥4 cm的结节的恶性率无差异。因此，不应仅基于结节大小就建议进行甲状腺切除术。
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