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神经梅毒：一例病例报告。

Neurosyphilis: a case report.

作者信息

Toptan Tugce, Ozdilek Betul, Kenangil Gulay, Ulker Mustafa, Domac Fusun Mayda

机构信息

Department of Neurology, Erenkoy Training and Research Hospital for Neurologic and Psychiatric Disorders, Istanbul, Turkey.

出版信息

North Clin Istanb. 2015 Apr 24;2(1):66-68. doi: 10.14744/nci.2015.96268. eCollection 2015.

DOI:10.14744/nci.2015.96268
PMID:28058343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5175054/
Abstract

Syphilis is a multisystem chronic infection caused by treponema pallidum. It can cause psychiatric disorders including depression, mania, psychosis, personality changes, delirium and dementia. With the introduction of penicillin into practice, the number of cases with syphilis decreased and its incidence increased with AIDS and HIV seropositivity. In this article, we present a case of neurosyphilis that manifested itself with neuropsychiatric symptoms.

摘要

梅毒是由梅毒螺旋体引起的多系统慢性感染。它可导致精神障碍，包括抑郁、躁狂、精神病、人格改变、谵妄和痴呆。随着青霉素应用于临床实践，梅毒病例数量减少，而随着艾滋病和HIV血清阳性率的上升，其发病率有所增加。在本文中，我们报告一例以神经精神症状表现的神经梅毒病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853c/5175054/5c89ae09cfec/NCI-2-66-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853c/5175054/5c89ae09cfec/NCI-2-66-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853c/5175054/5c89ae09cfec/NCI-2-66-g001.jpg

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本文引用的文献

1
Neurosyphilis. Screening does sometimes reveal an infectious cause of dementia.
Geriatrics. 2001 Mar;56(3):60-2.
2
Resolving the common clinical dilemmas of syphilis.解决梅毒常见的临床难题。
Am Fam Physician. 1999 Apr 15;59(8):2233-40, 2245-6.
3
Neurosyphilis in human immunodeficiency virus type 1-seropositive individuals. A prospective study.1型人类免疫缺陷病毒血清阳性个体中的神经梅毒。一项前瞻性研究。
Arch Neurol. 1991 Jul;48(7):700-2. doi: 10.1001/archneur.1991.00530190046014.
神经梅毒多种精神症状的叙述性综述：“伟大的模仿者”
Cureus. 2023 Sep 7;15(9):e44866. doi: 10.7759/cureus.44866. eCollection 2023 Sep.
4
Neurosyphilis in a young man having HIV infection, blurring of vision and skin rash.年轻男性感染 HIV 合并神经梅毒，出现视力模糊和皮疹。
J Postgrad Med. 2023 Oct-Dec;69(4):227-230. doi: 10.4103/jpgm.jpgm_484_22.
5
Clinical and laboratory features in patients with positive syphilis serology presenting with acute ischemic stroke or transient ischemic attack: a prospective cohort study.梅毒血清学阳性的急性缺血性脑卒中或短暂性脑缺血发作患者的临床和实验室特征：一项前瞻性队列研究。
BMC Infect Dis. 2022 Aug 30;22(1):717. doi: 10.1186/s12879-022-07700-z.
6
The Great Imitator: Latent Neurosyphilis Revealed After Initiation of the Immunosuppressive Drug Secukinumab.模仿大师：在开始使用免疫抑制药物司库奇尤单抗后发现潜伏性神经梅毒。
Cureus. 2021 Oct 3;13(10):e18462. doi: 10.7759/cureus.18462. eCollection 2021 Oct.
7
Response to Penicillin for Presumed Neurosyphilis in a Patient with Human Immunodeficiency Virus (HIV), a Normal CD4 Count, and an Undetectable Viral Load: A Case Report.对 HIV 感染者、CD4 计数正常且病毒载量不可检测者疑似神经梅毒应用青霉素治疗的反应：病例报告。
Am J Case Rep. 2021 Aug 11;22:e932467. doi: 10.12659/AJCR.932467.