Demirbas Soner, Kutlu Orkide, Kandemir Bahar, Sakin Abdullah
Department of Chest Diseases, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.
Department of Internal Medicine, Okmeydani Training and Research Hospital, Istanbul, Turkey.
North Clin Istanb. 2015 Sep 25;2(2):155-158. doi: 10.14744/nci.2015.04696. eCollection 2015.
Adult onset Still's disease is a rare systemic inflammatory disorder. At the onset of the disease sore throat, pharyngitis; which does not respond to antibiotics, one or two times peaking febrile episodes, marked salmon-colored rash on the trunk and extremities, arthralgia, arthritis, myalgia, fatigue, loss of appetite with nausea and weight loss; hepatosplenomegaly and lymphadenopathy can be seen. Among laboratory examinations levels of ferritin and other acute phase reactants distinctly rise, and neutrophilic leukocytosis; ANA and RF negativity are detected. Pleural and pericardial effusions, transient pulmonary infiltration, and rarely myocarditis can be seen during the course of the disease. Here we report a patient who was examined for fever of unknown origin and diagnosed with adult onset Still's disease which is a rare etiology of pleural effusion.
成人斯蒂尔病是一种罕见的全身性炎症性疾病。在疾病发作时，会出现喉咙痛、咽炎，对抗生素无反应，有一两次高热发作高峰，躯干和四肢出现明显的鲑鱼色皮疹、关节痛、关节炎、肌痛、疲劳、食欲不振伴恶心和体重减轻；可出现肝脾肿大和淋巴结病。在实验室检查中，铁蛋白和其他急性期反应物水平明显升高，且有中性粒细胞增多；抗核抗体（ANA）和类风湿因子（RF）呈阴性。在疾病过程中可出现胸腔和心包积液、短暂性肺部浸润，很少出现心肌炎。在此，我们报告一例因不明原因发热接受检查并被诊断为成人斯蒂尔病的患者，该病是胸腔积液的一种罕见病因。
