a Iranian Research Center on Aging , University of Social Welfare and Rehabilitation Sciences , Tehran , Iran.
b Malaysian Research Institute on Ageing (MyAgeing) , Universiti Putra Malaysia , Selangor , Malaysia.
Aging Ment Health. 2018 Apr;22(4):447-452. doi: 10.1080/13607863.2016.1268093. Epub 2017 Jan 6.
The negative effect of hypertension has overshadowed possible health problems associated with hypotension. The purposes of this study were to describe the prevalence of hypotension in older adults and to determine the association between hypotension and cognitive function, after adjusting for possible covariates.
The data for the study consisting of 1067 community-dwelling older adults were obtained from a national survey entitled "Identifying Psychosocial and Identifying Economic Risk Factor of Cognitive Impairment among Elderly", conducted in Malaysia. The hypotension was considered as blood pressure <120/75 mm Hg, measuring by standard mercury manometer. Data analysis was performed using the SPSS Version 22.0.
The mean age of the respondents was 68.27 (SD = 5.93). Mean score of cognitive function as measured by MMSE was 22.70 (SD = 4.95). The prevalence of hypotension was 29.3%. The prevalence of cognitive impairment for hypotension group was 25.6%. Results of multiple linear regression analysis revealed that hypotension is negatively associated with cognitive function (Beta = -0.11, p<.01), after adjusting for age, gender, education, marital status, employment status, diabetes, heart disease, stroke and gastritis.
The study showing hypotension is significantly associated with decreased cognitive function in later life, implies more attention to low blood pressure in old age.
高血压的负面影响已经掩盖了低血压可能带来的健康问题。本研究旨在描述老年人低血压的患病率，并在调整可能的协变量后，确定低血压与认知功能之间的关系。
该研究的数据来自于一项名为“识别老年人认知障碍的心理社会和经济风险因素”的全国性调查，共纳入 1067 名社区居住的老年人。采用标准汞柱血压计测量血压<120/75mmHg 来定义低血压。数据分析使用 SPSS 版本 22.0 进行。
受访者的平均年龄为 68.27（SD=5.93）。使用 MMSE 测量的认知功能平均得分为 22.70（SD=4.95）。低血压的患病率为 29.3%。低血压组认知障碍的患病率为 25.6%。多元线性回归分析结果表明，在调整年龄、性别、教育程度、婚姻状况、就业状况、糖尿病、心脏病、中风和胃炎后，低血压与认知功能呈负相关（β=-0.11，p<.01）。
本研究表明低血压与老年人认知功能下降显著相关，提示在老年时应更加关注低血压。
