优化认知障碍老年患者的药物治疗：基层医疗临床医生的考虑因素。
Optimizing medications in older adults with cognitive impairment: Considerations for primary care clinicians.
机构信息
Family physician at the Centre for Family Medicine Family Health Team in Kitchener, Ont, Schlegel Research Chair in Primary Care for Elders at the Schlegel-UW Research Institute for Aging, and Associate Clinical Professor in the Department of Family Medicine at McMaster University.
Pharmacist at the Centre for Family Medicine Family Health Team and Assistant Clinical Professor in the School of Pharmacy at the University of Waterloo in Ontario.
出版信息
Can Fam Physician. 2018 Sep;64(9):646-652.
OBJECTIVE
To provide primary care physicians with an approach to medication optimization in older adults with cognitive impairment.
SOURCES OF INFORMATION
The approach is based on an accredited memory clinic training program developed by the Centre for Family Medicine Primary Care Collaborative Memory Clinic.
MAIN MESSAGE
Dementia increases the risk of medication-related adverse events and adds to the complexity and challenge of providing optimal care for these older adults. Considerations include medication adherence, appropriate therapeutic targets for comorbid conditions, minimized use of medications with potentially adverse cognitive effects, and rational use and monitoring of cognition-enhancing drugs. Medication management plans must be individualized and based on goals of care.
CONCLUSION
Primary care physicians must consider many factors in optimizing medications for those with cognitive impairment.
目的
为初级保健医生提供一种方法，以优化认知障碍的老年患者的药物治疗。
信息来源
该方法基于家庭医学初级保健协作记忆诊所中心开发的认证记忆诊所培训计划。
主要信息
痴呆症增加了与药物相关的不良事件的风险，并增加了为这些老年人提供最佳护理的复杂性和挑战。需要考虑的因素包括药物依从性、合并症的适当治疗目标、尽量减少使用可能对认知产生不良影响的药物，以及合理使用和监测认知增强药物。药物管理计划必须个体化，并基于护理目标。
结论
初级保健医生在优化认知障碍患者的药物治疗时必须考虑许多因素。
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