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优化认知障碍老年患者的药物治疗:基层医疗临床医生的考虑因素。

Optimizing medications in older adults with cognitive impairment: Considerations for primary care clinicians.

机构信息

Family physician at the Centre for Family Medicine Family Health Team in Kitchener, Ont, Schlegel Research Chair in Primary Care for Elders at the Schlegel-UW Research Institute for Aging, and Associate Clinical Professor in the Department of Family Medicine at McMaster University.

Pharmacist at the Centre for Family Medicine Family Health Team and Assistant Clinical Professor in the School of Pharmacy at the University of Waterloo in Ontario.

出版信息

Can Fam Physician. 2018 Sep;64(9):646-652.

PMID:30209094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6135130/
Abstract

OBJECTIVE

To provide primary care physicians with an approach to medication optimization in older adults with cognitive impairment.

SOURCES OF INFORMATION

The approach is based on an accredited memory clinic training program developed by the Centre for Family Medicine Primary Care Collaborative Memory Clinic.

MAIN MESSAGE

Dementia increases the risk of medication-related adverse events and adds to the complexity and challenge of providing optimal care for these older adults. Considerations include medication adherence, appropriate therapeutic targets for comorbid conditions, minimized use of medications with potentially adverse cognitive effects, and rational use and monitoring of cognition-enhancing drugs. Medication management plans must be individualized and based on goals of care.

CONCLUSION

Primary care physicians must consider many factors in optimizing medications for those with cognitive impairment.

摘要

目的

为初级保健医生提供一种方法,以优化认知障碍的老年患者的药物治疗。

信息来源

该方法基于家庭医学初级保健协作记忆诊所中心开发的认证记忆诊所培训计划。

主要信息

痴呆症增加了与药物相关的不良事件的风险,并增加了为这些老年人提供最佳护理的复杂性和挑战。需要考虑的因素包括药物依从性、合并症的适当治疗目标、尽量减少使用可能对认知产生不良影响的药物,以及合理使用和监测认知增强药物。药物管理计划必须个体化,并基于护理目标。

结论

初级保健医生在优化认知障碍患者的药物治疗时必须考虑许多因素。

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本文引用的文献

1
Primary Care Collaborative Memory Clinics: Building Capacity for Optimized Dementia Care.初级保健协作记忆诊所:提升优化痴呆症护理的能力。
Healthc Q. 2017;19(4):55-62. doi: 10.12927/hcq.2017.25011.
2
A U-shaped Association Between Blood Pressure and Cognitive Impairment in Chinese Elderly.中国老年人血压与认知障碍之间的U型关联。
J Am Med Dir Assoc. 2017 Feb 1;18(2):193.e7-193.e13. doi: 10.1016/j.jamda.2016.11.011.
3
Benefits and Harms of Intensive Blood Pressure Treatment in Adults Aged 60 Years or Older: A Systematic Review and Meta-analysis.老年人(年龄≥60 岁)强化降压治疗的获益与危害:系统评价与荟萃分析。
Ann Intern Med. 2017 Mar 21;166(6):419-429. doi: 10.7326/M16-1754. Epub 2017 Jan 17.
4
The Treatment of Primary Orthostatic Hypotension.原发性直立性低血压的治疗
Ann Pharmacother. 2017 May;51(5):417-428. doi: 10.1177/1060028016689264. Epub 2017 Jan 16.
5
Prevalence of hypotension and its association with cognitive function among older adults.老年人低血压的患病率及其与认知功能的关系。
Aging Ment Health. 2018 Apr;22(4):447-452. doi: 10.1080/13607863.2016.1268093. Epub 2017 Jan 6.
6
Benzodiazepine Use and Risk of Dementia in the Elderly Population: A Systematic Review and Meta-Analysis.老年人中苯二氮䓬类药物的使用与痴呆症风险:一项系统评价和荟萃分析。
Neuroepidemiology. 2016;47(3-4):181-191. doi: 10.1159/000454881. Epub 2016 Dec 24.
7
Association between Benzodiazepine Use and Dementia: Data Mining of Different Medical Databases.苯二氮䓬类药物使用与痴呆症之间的关联:不同医学数据库的数据挖掘
Int J Med Sci. 2016 Oct 18;13(11):825-834. doi: 10.7150/ijms.16185. eCollection 2016.
8
Cognitive function and adherence to anticoagulation treatment in patients with atrial fibrillation.心房颤动患者的认知功能与抗凝治疗依从性
J Geriatr Cardiol. 2016 Jul;13(7):559-65. doi: 10.11909/j.issn.1671-5411.2016.07.006.
9
Antipsychotic use in dementia: a systematic review of benefits and risks from meta-analyses.痴呆症中抗精神病药物的使用:来自荟萃分析的益处和风险的系统评价
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Acetylcholinesterase inhibitors are associated with weight loss in older people with dementia: a systematic review and meta-analysis.乙酰胆碱酯酶抑制剂与老年痴呆症患者体重减轻相关:系统评价和荟萃分析。
J Neurol Neurosurg Psychiatry. 2016 Dec;87(12):1368-1374. doi: 10.1136/jnnp-2016-313660. Epub 2016 Jun 3.