中脑多巴胺神经元的测序标记。
Seq-ing Markers of Midbrain Dopamine Neurons.
机构信息
Neuroregeneration Research Institute, McLean Hospital / Harvard Medical School, Belmont, MA 02478, USA.
Neuroregeneration Research Institute, McLean Hospital / Harvard Medical School, Belmont, MA 02478, USA.
出版信息
Cell Stem Cell. 2017 Jan 5;20(1):11-12. doi: 10.1016/j.stem.2016.12.014.
Transplantation of human pluripotent stem cell-derived dopaminergic neurons is a promising approach to treating Parkinson's disease. In this issue of Cell Stem Cell, Kee et al. (2017) and Kirkeby et al. (2017) identify specific markers of midbrain dopaminergic progenitors to improve their derivation and predict dopamine neuron content after engraftment.
人多能干细胞源性多巴胺能神经元移植是治疗帕金森病的一种很有前途的方法。在本期的《Cell Stem Cell》杂志上，Kee 等人（2017 年）和 Kirkeby 等人（2017 年）确定了中脑神经祖细胞的特定标志物，以改善其衍生，并预测植入后多巴胺神经元的含量。
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