Kim Soonjoon, Lee Sun-Ho, Kim Eun-Sang, Eoh Whan
Department of Neurosurgery, Spine Center, Samsung Medical Center Sungkyunkwan University, School of Medicine, Seoul, Korea.
College of Medicine, Seonam University, Namwon, Korea.
J Korean Neurosurg Soc. 2017 Jan 1;60(1):114-117. doi: 10.3340/jkns.2014.1011.019. Epub 2016 Dec 29.
A 42-year-old man was admitted to our hospital with complaints of low back pain and intermittent right thigh pain. Twelve weeks before admission, the patient received intradiscal electrothermal therapy (IDET) at a local hospital. The patient still reported low back pain after the procedure that was managed with narcotic analgesics. Follow-up magnetic resonance imaging (MRI) was performed, and his referring physician thought the likely diagnosis was spondylodiscitis at the L4-5 spinal segment with a small epidural abscess. At admission to our department, the patient reported aggravated low back pain. Blood test results, including the erythrocyte sedimentation rate and C-reactive protein levels, were slightly elevated. Biopsy samples of the L4, L5 vertebral bodies and disk were obtained. The material underwent aerobic, anaerobic, fungal, mycobacterial cultures and histologic examination. Results of all cultures were negative. Histologically, necrosis of the bone was evident from the number of empty osteocyte lacunae. In addition, there was no evidence of infection based on biopsy results. No antibiotic treatment was administered on discharge. Repeat computed tomography and MRI performed 12 months after IDET showed a bony defect in the L4 and L5 vertebral bodies, and a decrease in the size of the L4-5 intervertebral disc lesion. We report a case of lumbar vertebral osteonecrosis induced by IDET and discuss etiology and radiologic features.
一名42岁男性因腰痛和右大腿间歇性疼痛入院。入院前12周,该患者在当地医院接受了椎间盘内电热疗法(IDET)。术后患者仍有腰痛,使用麻醉性镇痛药治疗。进行了随访磁共振成像(MRI)检查,其转诊医生认为可能的诊断是L4 - 5脊柱节段的脊椎椎间盘炎伴小的硬膜外脓肿。入院到我科时,患者报告腰痛加重。血液检查结果,包括红细胞沉降率和C反应蛋白水平略有升高。获取了L4、L5椎体及椎间盘的活检样本。样本进行了需氧、厌氧、真菌、分枝杆菌培养及组织学检查。所有培养结果均为阴性。组织学上,从空的骨陷窝数量可明显看出骨坏死。此外,根据活检结果没有感染迹象。出院时未给予抗生素治疗。IDET术后12个月重复进行的计算机断层扫描和MRI显示L4和L5椎体有骨缺损,L4 - 5椎间盘病变大小减小。我们报告一例由IDET引起的腰椎骨坏死病例,并讨论其病因及影像学特征。