Vuong Winston, Lin Jessica, Wei Randy L
Department of Radiation Oncology, Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA, USA.
Ann Palliat Med. 2017 Apr;6(2):165-172. doi: 10.21037/apm.2016.11.10. Epub 2016 Dec 19.
Palliative radiotherapy (PRT) improves patient quality of life (QoL) through alleviating cancer-associated symptoms such as pain, bleeding, and ulceration. Palliative management of patients with skin malignancies requires consideration of cosmetic and psychosocial outcomes as QoL measures. In this review, we highlight the current literature and advances in the use of PRT for patients with the three most commonly encountered forms of skin malignancies: basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma. The disease course and sensitivity to radiation varies, thus dictating the palliative goal and scheduling for PRT.
姑息性放疗(PRT)通过减轻疼痛、出血和溃疡等癌症相关症状来提高患者的生活质量(QoL)。皮肤恶性肿瘤患者的姑息治疗需要考虑美容和心理社会结果作为生活质量衡量指标。在本综述中,我们重点介绍了目前关于PRT用于三种最常见皮肤恶性肿瘤患者的文献及进展:基底细胞癌(BCC)、鳞状细胞癌(SCC)和黑色素瘤。疾病进程和对放疗的敏感性各不相同,因此决定了PRT的姑息治疗目标和疗程安排。