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使用CAD工具对甲状腺激素分泌机制进行优化的现场可编程门阵列(FPGA)实现

Optimized FPGA Implementation of the Thyroid Hormone Secretion Mechanism Using CAD Tools.

作者信息

Alghazo Jaafar M

机构信息

Center of King Salman Endowed Chair of Information Security, Department of Computer Engineering and Science, Prince Mohammad Bin Fahd University, Alkhobar, Kingdom of Saudi Arabia.

出版信息

J Med Syst. 2017 Feb;41(2):35. doi: 10.1007/s10916-016-0680-5. Epub 2017 Jan 6.

DOI:10.1007/s10916-016-0680-5
PMID:28063016
Abstract

The goal of this paper is to implement the secretion mechanism of the Thyroid Hormone (TH) based on bio-mathematical differential eqs. (DE) on an FPGA chip. Hardware Descriptive Language (HDL) is used to develop a behavioral model of the mechanism derived from the DE. The Thyroid Hormone secretion mechanism is simulated with the interaction of the related stimulating and inhibiting hormones. Synthesis of the simulation is done with the aid of CAD tools and downloaded on a Field Programmable Gate Arrays (FPGAs) Chip. The chip output shows identical behavior to that of the designed algorithm through simulation. It is concluded that the chip mimics the Thyroid Hormone secretion mechanism. The chip, operating in real-time, is computer-independent stand-alone system.

摘要

本文的目标是基于生物数学微分方程(DE)在FPGA芯片上实现甲状腺激素(TH)的分泌机制。硬件描述语言(HDL)用于开发从微分方程推导而来的该机制的行为模型。甲状腺激素分泌机制通过相关刺激和抑制激素的相互作用进行模拟。借助CAD工具完成模拟的综合,并下载到现场可编程门阵列(FPGA)芯片上。芯片输出通过模拟显示出与设计算法相同的行为。得出的结论是,该芯片模拟了甲状腺激素分泌机制。该芯片实时运行,是独立于计算机的单机系统。

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J Med Syst. 2016 Mar;40(3):63. doi: 10.1007/s10916-015-0404-2. Epub 2015 Dec 15.
2
FPGA Implementation of Heart Rate Monitoring System.心率监测系统的现场可编程门阵列实现
J Med Syst. 2016 Mar;40(3):49. doi: 10.1007/s10916-015-0410-4. Epub 2015 Dec 7.
3
Synchronization Design and Error Analysis of Near-Infrared Cameras in Surgical Navigation.手术导航中近红外相机的同步设计与误差分析。
J Med Syst. 2016 Jan;40(1):7. doi: 10.1007/s10916-015-0368-2. Epub 2015 Oct 29.
4
Hardware System for Real-Time EMG Signal Acquisition and Separation Processing during Electrical Stimulation.电刺激过程中实时肌电信号采集与分离处理的硬件系统。
J Med Syst. 2015 Sep;39(9):88. doi: 10.1007/s10916-015-0267-6. Epub 2015 Jul 26.
5
A patient-specific model of the negative-feedback control of the hypothalamus-pituitary-thyroid (HPT) axis in autoimmune (Hashimoto's) thyroiditis.自身免疫性(桥本氏)甲状腺炎中下丘脑 - 垂体 - 甲状腺(HPT)轴负反馈控制的患者特异性模型。
Math Med Biol. 2014 Sep;31(3):226-58. doi: 10.1093/imammb/dqt005. Epub 2013 May 2.
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Gender-specific regulation of response to thyroid hormone in aging.衰老过程中甲状腺激素反应的性别特异性调节。
Thyroid Res. 2012 Jan 26;5(1):1. doi: 10.1186/1756-6614-5-1.
7
Synthesis of the Growth Hormone Secretion Mechanism Using Nonlinear Analysis and CAD Tools.使用非线性分析和计算机辅助设计工具合成生长激素分泌机制
Conf Proc IEEE Eng Med Biol Soc. 2005;2005:4650-3. doi: 10.1109/IEMBS.2005.1615507.
8
Thyroid disease.甲状腺疾病
Br J Anaesth. 2000 Jul;85(1):15-28. doi: 10.1093/bja/85.1.15.