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90岁及以上患者头颈部游离皮瓣重建的发病率和功能结果

Morbidity and Functional Outcomes With Head and Neck Free Flap Reconstruction in Patients Aged 90 Years or Older.

作者信息

Fagin Adam P, Gelesko Savannah, Wax Mark K, Petrisor Daniel

机构信息

Oral and Maxillofacial Surgery Resident, Department of Oral and Maxillofacial Surgery, Oregon Health and Science University, Portland, OR.

Microvascular Surgery Fellow, Department of Otolaryngology, Oregon Health and Science University, Portland, OR.

出版信息

J Oral Maxillofac Surg. 2017 Jul;75(7):1549-1554. doi: 10.1016/j.joms.2016.12.015. Epub 2016 Dec 18.

Abstract

PURPOSE

Morbidity of free tissue transfer in the extremes of age is controversial and not well studied in patients aged 90 years or older because of the rarity of these patients and many clinicians' natural hesitancy to perform such a large operation in patients of this group. The purpose of this study was to answer the following clinical question: Do patients aged 90 years or older who undergo free flap reconstruction have worse functional outcomes than their younger counterparts?

MATERIALS AND METHODS

We performed a retrospective chart review of patients aged 90 years or older who underwent free flap reconstruction at Oregon Health and Science University Hospital from 2000 to 2015. All patients aged 90 years or older undergoing free flap reconstruction were included. Patients younger than 90 years during the same period were randomly selected to serve as controls.

RESULTS

Free flap reconstructions were performed in 14 patients aged 90 years or older, who were then compared with their randomly selected controls. The only statistically significant difference observed in the outcome variables analyzed was the location of discharge from the hospital, with the older patients more likely to be discharged to a skilled nursing facility (P = .002). However, there was no difference in return-to-baseline level of care at last follow-up between the 2 groups. There also was no statistically significant difference in major or minor medical or surgical complication rates, duration of hospitalization, duration of tracheostomy, return to baseline respiratory status, or return to baseline feeding status between the 2 groups.

CONCLUSIONS

Patients aged 90 years or older are more likely to be discharged to a skilled nursing facility than their younger counterparts, but otherwise have similar outcomes in terms of complications and return to baseline function. The results of this study suggest that age 90 years or older should not be a direct contraindication for free flap reconstruction in the head and neck.

摘要

目的

在年龄极大的患者中进行游离组织移植的发病率存在争议,且对于90岁及以上的患者尚未得到充分研究,因为这类患者较为罕见,并且许多临床医生自然会对该年龄段的患者进行如此大型的手术有所顾虑。本研究的目的是回答以下临床问题:接受游离皮瓣重建的90岁及以上患者的功能结局是否比年轻患者更差?

材料与方法

我们对2000年至2015年在俄勒冈健康与科学大学医院接受游离皮瓣重建的90岁及以上患者进行了回顾性病历审查。纳入了所有90岁及以上接受游离皮瓣重建的患者。随机选择同期年龄小于90岁的患者作为对照。

结果

对14名90岁及以上的患者进行了游离皮瓣重建,然后将他们与其随机选择的对照进行比较。在分析的结局变量中观察到的唯一具有统计学意义的差异是出院地点,老年患者更有可能出院到专业护理机构(P = .002)。然而,两组在最后一次随访时恢复到基线护理水平方面没有差异。两组在主要或次要医疗或手术并发症发生率、住院时间、气管切开时间、恢复到基线呼吸状态或恢复到基线喂养状态方面也没有统计学意义的差异。

结论

90岁及以上的患者比年轻患者更有可能出院到专业护理机构,但在并发症和恢复到基线功能方面的结局相似。本研究结果表明,90岁及以上不应成为头颈部游离皮瓣重建的直接禁忌证。

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