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接受游离皮瓣重建的老年患者的发病率与生存率:一项回顾性队列研究。

Morbidity and Survival in Elderly Patients Undergoing Free Flap Reconstruction: A Retrospective Cohort Study.

作者信息

Mitchell Candace A, Goldman Richard A, Curry Joseph M, Cognetti David M, Krein Howard, Heffelfinger Ryan, Luginbuhl Adam

机构信息

1 Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Otolaryngol Head Neck Surg. 2017 Jul;157(1):42-47. doi: 10.1177/0194599817696301. Epub 2017 Mar 7.

Abstract

Objective To review a single institution's outcomes of free flap reconstruction of the head and neck in patients aged ≥80 years as compared with those <80 years. Study Design Retrospective cohort study. Setting Tertiary academic hospital. Subjects and Methods Patients aged ≥ 80 years who underwent free flap reconstruction of the head and neck between 2007 and 2013 were identified and matched by type of reconstruction with a cohort of younger patients. Outcome measures included flap success, length of stay, discharge disposition, complications, and 2-year mortality. Associations between complications and comorbidities were also evaluated. Results Sixty-six patients aged ≥80 years were identified, and a paired sample <80 years old was selected. There were 3 flap failures per group and 1 perioperative mortality in the elderly group. There was no significant difference in length of stay or major complications between groups. Significantly more elderly patients were discharged to a nursing facility. There was no significant difference in mortality rates at 2 years postoperatively. No associations were seen between level of comorbidity and complications among the elderly group. Conclusion Free flap reconstruction of the head and neck remains a viable option in patients of advanced age. Similar outcomes in terms of flap success, complications, and length of hospitalization can be achieved as compared with younger patients undergoing similar reconstructions. The role of comorbid disease as a predictor of complications remains unclear. There is no significant difference in 2-year mortality for elderly free flap patients versus younger controls.

摘要

目的 回顾一家机构中年龄≥80岁的患者与年龄<80岁的患者相比,头颈部游离皮瓣重建的结果。研究设计 回顾性队列研究。研究地点 三级学术医院。研究对象和方法 确定2007年至2013年间接受头颈部游离皮瓣重建的年龄≥80岁的患者,并根据重建类型与一组年轻患者进行匹配。观察指标包括皮瓣成功率、住院时间、出院去向、并发症和2年死亡率。还评估了并发症与合并症之间的关联。结果 确定了66例年龄≥80岁的患者,并选择了一组配对的<80岁的样本。每组有3例皮瓣失败,老年组有1例围手术期死亡。两组之间的住院时间或主要并发症无显著差异。显著更多的老年患者出院后入住护理机构。术后2年的死亡率无显著差异。老年组中合并症水平与并发症之间未见关联。结论 头颈部游离皮瓣重建对高龄患者仍然是一种可行的选择。与接受类似重建的年轻患者相比,在皮瓣成功率、并发症和住院时间方面可取得相似的结果。合并症作为并发症预测指标的作用仍不明确。老年游离皮瓣患者与年轻对照组相比,2年死亡率无显著差异。

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