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室内灰尘中短链和中链氯化石蜡浓度:对人体暴露的影响。

Concentrations of short- and medium-chain chlorinated paraffins in indoor dusts from malls in China: Implications for human exposure.

机构信息

Dalian Institute of Chemical Physics Chinese Academy of Sciences, Dalian 116023, China; Shenyang Pharmaceutical University, Shenyang 110016, China.

Dalian Institute of Chemical Physics Chinese Academy of Sciences, Dalian 116023, China.

出版信息

Chemosphere. 2017 Apr;172:103-110. doi: 10.1016/j.chemosphere.2016.12.150. Epub 2017 Jan 2.

Abstract

Levels and distribution of short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) were measured in indoor dusts from malls in China. The concentrations of SCCPs and MCCPs in dustfalls from a building material mall ranged from 6.0 to 361.4 μg g and from 5.0 to 285.9 μg g, respectively. Much heavier contamination was found in central air conditioner filter (CACF) dusts from a newly opened shopping mall, with SCCP concentrations of 114.7-707.0 μg g and MCCP concentrations of 89.0-1082.9 μg g. The C- and C-CPs were the dominant congeners, while the Cl and Cl groups were the major chlorine congeners in both kinds of dust samples. Significant correlation relationships (p ≤ 0.05) were found between ∑SCCPs and ∑MCCPs in CACF dusts and dustfalls. Varied exposure pathways including dust ingestion and dermal permeation have been evaluated. The average daily exposure doses of SCCPs and MCCPs for the adult in CACF dusts and dustfalls were estimated to be 0.394 and 0.150 μg kg day, respectively. The toddler had higher exposure risks with 5.918 and 2.658 μg kg day in the shopping and building material malls, respectively. Dermal permeation was the predominated exposure pathway for the adult, while dust ingestion was suggested to be more important for the toddler due to hand-to-mouth contact.

摘要

室内灰尘中的短链和中链氯化石蜡(SCCPs 和 MCCPs)的水平和分布在中国的商场进行了测量。建材商场扬尘中 SCCPs 和 MCCPs 的浓度范围分别为 6.0 至 361.4μg/g 和 5.0 至 285.9μg/g。在一家新开的购物中心的中央空调滤清器(CACF)灰尘中发现了更严重的污染,SCCP 浓度为 114.7-707.0μg/g,MCCP 浓度为 89.0-1082.9μg/g。C-和 C-CPs 是主要的同系物,而 Cl 和 Cl 组是这两种灰尘样品中的主要氯同系物。CACF 灰尘和扬尘中 SCCPs 和 MCCPs 的总和之间存在显著的相关性(p≤0.05)。已经评估了包括灰尘摄入和皮肤渗透在内的不同暴露途径。CACF 灰尘和扬尘中成人的 SCCPs 和 MCCPs 的平均日暴露剂量估计分别为 0.394 和 0.150μg/kg/day。幼儿在购物中心和建材商场的暴露风险更高,分别为 5.918 和 2.658μg/kg/day。皮肤渗透是成人的主要暴露途径,而由于手口接触,灰尘摄入对幼儿更为重要。

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