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二次阑尾切除术:针对穿孔性阑尾炎非手术治疗失败后的手术治疗。

Second date appendectomy: Operating for failure of nonoperative treatment in perforated appendicitis.

作者信息

Lotti Marco

机构信息

Advanced Surgical Oncology Unit, Department of General Surgery 1, Papa Giovanni XXIII Hospital, Bergamo, Italy.

出版信息

Am J Emerg Med. 2017 Jun;35(6):939.e3-939.e6. doi: 10.1016/j.ajem.2016.12.072. Epub 2017 Jan 2.

Abstract

BACKGROUND

Nonoperative treatment of acute appendicitis is embraced by many surgical teams, driven by low to moderate quality randomized studies that support noninferiority of antibiotics versus appendectomy for treatment of acute uncomplicated appendicitis. Several flaws of these studies have emerged, especially in the recruitment strategy and in the diagnostic criteria that were used. The growing confidence given to antibiotics, together with the lack of reliable criteria to distinguish between uncomplicated and perforated appendicitis, exposes patients with perforated appendicitis to the likelihood to be treated with antibiotics instead of surgery. Among them, those patients who experience a temporary relief of symptoms due to antibiotics, followed by early recurrence of disease when antibiotics are discontinued, are likely to undergo appendectomy at their second date. Second date appendectomy, i.e. the removal of the appendix when acute inflammation relapses within the scar of a previously unhealed perforated appendicitis, is the unwanted child of the nonoperative treatment and a new challenge for both the surgeon and the patient.

METHODS

Between June and July 2016, two patients were readmitted and operated for failure of nonoperative treatment with antibiotics.

RESULTS

A video is presented, which focuses on the different anatomic presentation and technical challenges between prompt and second date laparoscopic appendectomy.

CONCLUSIONS

When proposing nonoperative treatment for acute appendicitis, surgeons should be aware and inform their patients that if the appendix is perforated and an incomplete healing and early recurrence occur, a second date appendectomy could be a more challenging operation compared to a prompt appendectomy.

摘要

背景

许多外科团队都采用急性阑尾炎的非手术治疗方法,这是由低至中等质量的随机研究推动的,这些研究支持抗生素治疗与阑尾切除术在治疗急性单纯性阑尾炎方面具有非劣效性。这些研究出现了几个缺陷,特别是在招募策略和所使用的诊断标准方面。对抗生素的信心日益增强,加上缺乏区分单纯性阑尾炎和穿孔性阑尾炎的可靠标准,使穿孔性阑尾炎患者有可能接受抗生素治疗而非手术治疗。其中,那些因抗生素治疗而症状暂时缓解,但在停用抗生素后疾病早期复发的患者,可能会在第二次就诊时接受阑尾切除术。第二次阑尾切除术,即在先前未愈合的穿孔性阑尾炎瘢痕内急性炎症复发时切除阑尾,是非手术治疗中不受欢迎的结果,对外科医生和患者来说都是新的挑战。

方法

2016年6月至7月期间,两名患者因抗生素非手术治疗失败再次入院并接受手术。

结果

展示了一段视频,重点介绍了初次和第二次腹腔镜阑尾切除术之间不同的解剖表现和技术挑战。

结论

在提出急性阑尾炎的非手术治疗方案时,外科医生应意识到并告知患者,如果阑尾穿孔且愈合不完全并早期复发,与初次阑尾切除术相比,第二次阑尾切除术可能是一项更具挑战性的手术。

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