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潜在不适当用药处方与社会经济因素相关:法国北部加来海峡地区的空间分析。

Potentially inappropriate medication prescribing is associated with socioeconomic factors: a spatial analysis in the French Nord-Pas-de-Calais Region.

作者信息

Beuscart Jean-Baptiste, Genin Michael, Dupont Corrine, Verloop David, Duhamel Alain, Defebvre Marguerite-Marie, Puisieux François

机构信息

Univ. Lille, EA 2694 - Santé publique: épidémiologie et qualité des soins, F-59000 Lille, France.

CHU Lille, Geriatric Department, F-59000 Lille, France.

出版信息

Age Ageing. 2017 Jul 1;46(4):607-613. doi: 10.1093/ageing/afw245.

Abstract

BACKGROUND

potentially inappropriate medication (PIM) prescribing is common in older people and leads to adverse events and hospital admissions.

OBJECTIVE

to determine whether prevalence of PIM prescribing varies according to healthcare supply and socioeconomic status.

METHODS

all prescriptions dispensed at community pharmacies for patients aged 75 and older between 1 January  and 31 March 2012 were retrieved from French Health Insurance Information System of the Nord-Pas-de-Calais Region for patients affiliated to the Social Security scheme. PIM was defined according to the French list of Laroche. The geographic distribution of PIM prescribing in this area was analysed using spatial scan statistics.

RESULTS

overall, 65.6% (n = 207,979) of people aged 75 years and over living in the Nord-Pas-de-Calais Region were included. Among them, 32.6% (n = 67,863) received at least one PIM. The spatial analysis identified 16 and 10 clusters of municipalities with a high and a low prevalence of PIM prescribing, respectively. Municipalities with a low prevalence of PIM were characterised by a high socioeconomic status whereas those with a high prevalence of PIM were mainly characterised by a low socioeconomic status, such as a high unemployment rate and low household incomes. Markers of healthcare supply were weakly associated with high or low prevalence clusters.

CONCLUSION

significant geographic variation in PIM prescribing was observed in the study territory and was mainly associated with socioeconomic factors.

摘要

背景

潜在不适当用药(PIM)处方在老年人中很常见,并会导致不良事件和住院治疗。

目的

确定PIM处方的流行率是否因医疗供应和社会经济地位而异。

方法

从法国北部加来海峡地区医疗保险信息系统中检索2012年1月1日至3月31日期间社区药房为75岁及以上参加社会保障计划患者配药的所有处方。PIM根据法国拉罗什清单定义。使用空间扫描统计分析该地区PIM处方的地理分布。

结果

总体而言,纳入了居住在北部加来海峡地区的65.6%(n = 207,979)的75岁及以上人群。其中,32.6%(n = 67,863)接受了至少一种PIM。空间分析分别确定了16个PIM处方高流行率和10个低流行率的市镇集群。PIM低流行率的市镇的特点是社会经济地位高,而PIM高流行率的市镇主要特点是社会经济地位低,如高失业率和低家庭收入。医疗供应指标与高或低流行率集群的关联较弱。

结论

在研究区域观察到PIM处方存在显著的地理差异,且主要与社会经济因素相关。

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