巴西南里奥格兰德州欧洲-非洲裔和日本裔人群人类血小板抗原的遗传多态性。
Genetic polymorphisms of human platelet antigens in Euro-African and Japanese descendants from Parana, Southern Brazil.
机构信息
a Post Graduation Program of Biosciences and Physiopathology, Biomedicine and Clinical Analysis Department , Maringa State University , Maringa , Brazil.
b Albert Einstein Israelita Hospital , São Paulo , Brazil.
出版信息
Platelets. 2017 Sep;28(6):607-610. doi: 10.1080/09537104.2016.1257785. Epub 2017 Jan 9.
The frequency distributions of HPA-1 to HPA-6 and HPA-15 were evaluated in two Brazilian populations from Parana: a mixed population of predominantly Caucasians and a population of Japanese descendants. Genotyping was performed by PCR-SSP in 364 unrelated individuals. Differences in the distribution of HPA highlight diversity in Brazilian miscegenation and the importance of formation of the HPA panel composed of regional blood donors.
评估了来自巴西巴拉那州的两个群体中的 HPA-1 至 HPA-6 和 HPA-15 的频率分布：一个主要是白种人的混合群体和一个日本后裔群体。通过 PCR-SSP 在 364 个无关个体中进行基因分型。HPA 分布的差异突出了巴西混合人群的多样性，以及由区域献血者组成的 HPA 面板形成的重要性。
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