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探讨老年人肥胖与睡眠时长之间的双向关联:英国老龄化纵向研究(ELSA)。

Investigating the Bidirectional Associations of Adiposity with Sleep Duration in Older Adults: The English Longitudinal Study of Ageing (ELSA).

机构信息

Department of Epidemiology &Public Health, University College London, UK.

Institute for Social &Economic Research, University of Essex, UK.

出版信息

Sci Rep. 2017 Jan 9;7:40250. doi: 10.1038/srep40250.

DOI:10.1038/srep40250
PMID:28067295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5220373/
Abstract

Cross-sectional analyses of adiposity and sleep duration in younger adults suggest that increased adiposity is associated with shorter sleep. Prospective studies have yielded mixed findings, and the direction of this association in older adults is unclear. We examined the cross-sectional and potential bi-directional, prospective associations between adiposity and sleep duration (covariates included demographics, health behaviours, and health problems) in 5,015 respondents from the English Longitudinal Study of Ageing (ELSA), at baseline and follow-up. Following adjustment for covariates, we observed no significant cross-sectional relationship between body mass index (BMI) and sleep duration [(unstandardized) B = -0.28 minutes, (95% Confidence Intervals (CI) = -0.012; 0.002), p = 0.190], or waist circumference (WC) and sleep duration [(unstandardized) B = -0.10 minutes, (95% CI = -0.004; 0.001), p = 0.270]. Prospectively, both baseline BMI [B = -0.42 minutes, (95% CI = -0.013; -0.002), p = 0.013] and WC [B = -0.18 minutes, (95% CI = -0.005; -0.000), p = 0.016] were associated with decreased sleep duration at follow-up, independently of covariates. There was, however, no association between baseline sleep duration and change in BMI or WC (p > 0.05). In older adults, our findings suggested that greater adiposity is associated with decreases in sleep duration over time; however the effect was very small.

摘要

横断面分析表明,年轻人的肥胖和睡眠时间与睡眠时间较短有关。前瞻性研究得出的结果喜忧参半,老年人中这种关联的方向尚不清楚。我们在基线和随访时,使用英国老龄化纵向研究(ELSA)中的 5015 名受访者的横断面和潜在双向前瞻性数据,研究了肥胖和睡眠时间之间的关系(协变量包括人口统计学,健康行为和健康问题)。调整协变量后,我们没有观察到体重指数(BMI)和睡眠时间之间存在显著的横断面关系[(未标准化)B = -0.28 分钟,(95%置信区间(CI)= -0.012; 0.002),p = 0.190],或腰围(WC)和睡眠时间[(未标准化)B = -0.10 分钟,(95%CI = -0.004; 0.001),p = 0.270]。前瞻性地,基线 BMI [B = -0.42 分钟,(95%CI = -0.013; -0.002),p = 0.013]和 WC [B = -0.18 分钟,(95%CI = -0.005; -0.000),p = 0.016]与随访时睡眠持续时间的减少独立相关,独立于协变量。但是,基线睡眠持续时间与 BMI 或 WC 的变化之间没有关联(p> 0.05)。在老年人中,我们的发现表明,随着时间的流逝,肥胖程度越大,睡眠时间越短;但是这种影响非常小。

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