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炎症性肠病的手术治疗可以个体化吗?

Can Surgery for Inflammatory Bowel Disease be Personalized?

机构信息

Department of Biomedical Sciences, Humanitas University, via Manzoni 113, 20089 Rozzano, Milano, Italy.

Colon and Rectal Surgery Unit, Department of Surgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.

出版信息

Curr Drug Targets. 2018;19(7):798-804. doi: 10.2174/1389450118666170105153646.

DOI:10.2174/1389450118666170105153646
PMID:28068895
Abstract

BACKGROUND

In the treatment of Inflammatory Bowel Diseases (IBD) despite advances in medical therapies, surgery has maintained a leading role in the management of complications of the disease, as well as in cases of failure of medical therapy.

OBJECTIVE

discuss the possible role for a personalization in debated fields of surgical treatment of Crohn's disease and ulcerative colitis.

CONCLUSIONS

Surgery has become more and more minimally invasive, struggling for a difficult balance between guidelines and personalized treatment tailored on the single patient's need. There is no room for fixed management for surgery in IBD. A tailored approach is key to better outcome in each specific patient.

摘要

背景

尽管在医学治疗方面取得了进步,但在炎症性肠病(IBD)的治疗中,手术仍然在疾病并发症的治疗以及药物治疗失败的情况下发挥着主要作用。

目的

讨论在克罗恩病和溃疡性结肠炎的有争议的手术治疗领域中实现个体化治疗的可能。

结论

手术已经变得越来越微创,在指南和针对单个患者需求的个体化治疗之间艰难地寻求平衡。在 IBD 中,手术的固定管理没有空间。针对每个特定患者的个体化方法是获得更好结果的关键。

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