Peterson L G, Bongar B
Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655.
Gen Hosp Psychiatry. 1989 Nov;11(6):412-7. doi: 10.1016/0163-8343(89)90136-9.
A single blind study design was used to evaluate the efficacy and safety of Navane versus Haldol in acute organic mental syndromes in a general hospital setting. Seventeen patients were entered into the study; only 14 remained in the study long enough to complete the protocol. Most patients treated with either neuroleptic agent improved. Only one patient was worse. Improvement occurred rapidly (2-3 days), and few significant side effects were observed. There was a trend toward lower BPRS scores in patients treated with Navane (thiothixene).
