Balon R, Berchou R, Zethelius M
Can J Psychiatry. 1987 Mar;32(2):149-50. doi: 10.1177/070674378703200213.
Hematological side effects of neuroleptic drugs occur infrequently but remain a potential cause of serious toxicity. A case of recurrent thrombocytopenia due to the repeated exposure to chlorpromazine (twice), haloperidol (four times) and thiothixene (twice) in a 59 year old female treated for schizophrenia is reported. Treatment difficulties and implications of this case are discussed.
抗精神病药物的血液学副作用虽不常见,但仍是严重毒性的潜在原因。本文报告了一例59岁女性精神分裂症患者,因反复使用氯丙嗪(两次)、氟哌啶醇(四次)和硫利达嗪(两次)而出现复发性血小板减少症的病例。文中讨论了该病例的治疗难点及影响。