Du Yina, Kitzmiller Joseph A, Sridharan Anusha, Perl Anne K, Bridges James P, Misra Ravi S, Pryhuber Gloria S, Mariani Thomas J, Bhattacharya Soumyaroop, Guo Minzhe, Potter S Steven, Dexheimer Phillip, Aronow Bruce, Jobe Alan H, Whitsett Jeffrey A, Xu Yan
The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Department of Pediatrics, University of Rochester, Rochester, New York, USA.
Thorax. 2017 May;72(5):481-484. doi: 10.1136/thoraxjnl-2016-209598. Epub 2017 Jan 9.
'LungGENS', our previously developed web tool for mapping single-cell gene expression in the developing lung, has been well received by the pulmonary research community. With continued support from the 'LungMAP' consortium, we extended the scope of the LungGENS database to accommodate transcriptomics data from pulmonary tissues and cells from human and mouse at different stages of lung development. Lung Gene Expression Analysis (LGEA) web portal is an extended version of LungGENS useful for the analysis, display and interpretation of gene expression patterns obtained from single cells, sorted cell populations and whole lung tissues. The LGEA web portal is freely available at http://research.cchmc.org/pbge/lunggens/mainportal.html.
“LungGENS”是我们之前开发的用于绘制发育中肺脏单细胞基因表达图谱的网络工具，已受到肺部研究界的广泛欢迎。在“LungMAP”联盟的持续支持下，我们扩展了LungGENS数据库的范围，以纳入来自人类和小鼠不同肺发育阶段的肺组织和细胞的转录组学数据。肺基因表达分析（LGEA）网络门户是LungGENS的扩展版本，可用于分析、显示和解释从单细胞、分选的细胞群体和全肺组织获得的基因表达模式。LGEA网络门户可在http://research.cchmc.org/pbge/lunggens/mainportal.html免费获取。
