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一项关于磁控生长棒暴露于磁共振成像(MRI)后温度及邻近组织变化的尸体初步研究。

A pilot cadaveric study of temperature and adjacent tissue changes after exposure of magnetic-controlled growing rods to MRI.

作者信息

Poon Selina, Nixon Ryan, Wendolowski Stephen, Gecelter Rachel, Chen Yen Hsun, DiMauro Jon-Paul, Amaral Terry, Graver Adam, Grande Daniel A

机构信息

Department of Orthopaedics, Shriners Hospitals for Children, 3160 Geneva Street, Los Angeles, CA, 90020, USA.

Department of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.

出版信息

Eur Spine J. 2017 Jun;26(6):1618-1623. doi: 10.1007/s00586-016-4918-1. Epub 2017 Jan 9.

Abstract

PURPOSE

To test for possible thermal injury and tissue damage caused by magnetic-controlled growing rods (MCGRs) during MRI scans.

METHODS

Three fresh frozen cadavers were utilized. Four MRI scans were performed: baseline, after spinal hardware implantation, and twice after MCGR implantation. Cross connectors were placed at the proximal end and at the distal end of the construct, making a complete circuit hinged at those two points. Three points were identified as potential sites for significant heating: adjacent to the proximal and distal cross connectors and adjacent to the actuators. Data collected included tissue temperatures at baseline (R1), after screw insertion (R2), and twice after rod insertions (R3 and R4). Tissue samples were taken and stained for signs of heat damage.

RESULTS

There was a slight change in tissue temperature in the regions next to the implants between baseline and after each scan. Average temperatures (°C) increased by 0.94 (0.16-1.63) between R1 and R2, 1.6 (1.23-1.97) between R2 and R3, and 0.39 (0.03-0.83) between R3 and R4. Subsequent histological analysis revealed no signs of heat induced damage.

CONCLUSION

Recurrent MRI scans of patients with MCGRs may be necessary over the course of treatment. When implanted into human cadaveric tissue, these rods appear to not be a risk to the patient with respect to heating or tissue damage. Further in vivo study is warranted.

LEVEL OF EVIDENCE

N/A.

摘要

目的

检测在磁共振成像(MRI)扫描过程中,磁控生长棒(MCGRs)是否会造成潜在的热损伤和组织损伤。

方法

使用了三具新鲜冷冻尸体。进行了四次MRI扫描:基线扫描、脊柱内固定植入后扫描,以及MCGR植入后两次扫描。在构建物的近端和远端放置交叉连接器,形成一个在这两点铰接的完整回路。确定了三个可能出现显著发热的潜在部位:靠近近端和远端交叉连接器处以及靠近致动器处。收集的数据包括基线时(R1)、螺钉插入后(R2)以及棒插入后两次(R3和R4)的组织温度。采集组织样本并进行染色,以检测热损伤迹象。

结果

在每次扫描前后,植入物附近区域的组织温度有轻微变化。平均温度(°C)在R1和R2之间升高了0.94(0.16 - 1.63),在R2和R3之间升高了1.6(1.23 - 1.97),在R3和R4之间升高了0.39(0.03 - 0.83)。随后的组织学分析未发现热诱导损伤的迹象。

结论

在治疗过程中,可能有必要对植入MCGRs的患者进行反复的MRI扫描。当植入人体尸体组织时,这些棒似乎不会对患者造成加热或组织损伤风险。有必要进行进一步的体内研究。

证据水平

无。

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