Radovic Sara, Gordon Michael S, Melvin Glenn A
Centre of Developmental Psychiatry and Psychology, Department of Psychiatry, School of Clinical Sciences, Melbourne, Victoria, Australia.
Early in Life Mental Health Services, Monash Health, Melbourne, Victoria, Australia.
J Paediatr Child Health. 2017 Mar;53(3):214-220. doi: 10.1111/jpc.13426. Epub 2017 Jan 10.
There is growing interest in the potential role of exercise in the reduction of depressive symptoms. The aim of this meta-analysis was to examine whether exercise reduces depressive symptoms amongst depressed adolescents. The following databases were searched on 30 January 2015: MEDLINE, PsychINFO, SPORTDiscuss and PUBMED. Studies were included if they examined exercise interventions amongst adolescents with clinical levels of depressive symptoms, were published in peer-reviewed journals in the English language and contained a control/comparison group. Of 6631 retrieved studies, eight studies were included in the meta-analysis. Meta-analysis was conducted using a random effects model due to the high level of heterogeneity identified amongst studies ( I = 65.1, P < .005). The analysis revealed a moderate reduction in depressive symptoms post-intervention (Hedge's g = -0.61, P = .007). This analysis provides preliminary evidence that exercise is effective in reducing symptoms of depression among adolescents with clinical levels of depressive symptoms. The present meta-analysis, however, is limited by the generally low quality of included studies, high level of between-study heterogeneity and restriction of inclusion criteria to published studies. Further high-quality trials with depressed adolescents are needed to determine the efficacy of exercise in the reduction of depressive symptoms and the exercise parameters associated with the antidepressant effects of exercise.
运动在减轻抑郁症状方面的潜在作用正受到越来越多的关注。这项荟萃分析的目的是研究运动是否能减轻抑郁青少年的抑郁症状。2015年1月30日检索了以下数据库：MEDLINE、PsychINFO、SPORTDiscuss和PUBMED。如果研究考察了有临床抑郁症状水平的青少年的运动干预措施，以英文发表在同行评审期刊上且包含对照组/比较组，则纳入研究。在检索到的6631项研究中，有8项研究被纳入荟萃分析。由于研究间存在高度异质性（I = 65.1，P <.005），使用随机效应模型进行荟萃分析。分析显示干预后抑郁症状有中度减轻（Hedge's g = -0.61，P =.007）。该分析提供了初步证据，表明运动对减轻有临床抑郁症状水平的青少年的抑郁症状有效。然而，本荟萃分析受到纳入研究质量普遍较低、研究间异质性高以及纳入标准仅限于已发表研究的限制。需要对抑郁青少年进行进一步的高质量试验，以确定运动在减轻抑郁症状方面的疗效以及与运动抗抑郁作用相关的运动参数。
