Calmettes C
INSERM U. 113, Paris, France.
Horm Metab Res Suppl. 1989;21:1-2.
Screening of medullary cancer of the thyroid (MCT) in France relies on a collaborative work since 1982. The diagnosis of the index case relies on the detection of calcitonin in the tumor as well as on assay of circulating CT. A common protocol is used for patients and families. The familial screening is systematically carried out, even in apparently sporadic MCTs. A pentagastrin CT stimulation test is asked for all family members, whatever the age. All the data are collected by regional coordinators and centralized in a national register. Until 1987, 1031 MCT cases have been recorded, including 226 familial cases belonging to 62 families (29 MCT only, 29 MEN IIa and 4 MEN IIb).
自1982年以来，法国甲状腺髓样癌（MCT）的筛查依靠协作开展。索引病例的诊断依赖于肿瘤中降钙素的检测以及循环CT的测定。针对患者及其家属采用统一方案。即使是明显散发的MCT病例，也会系统性地进行家族筛查。无论年龄大小，所有家庭成员都要进行五肽胃泌素CT刺激试验。所有数据由地区协调员收集并集中录入国家登记册。截至1987年，已记录1031例MCT病例，其中包括属于62个家系的226例家族性病例（仅29例MCT、29例MEN IIa和4例MEN IIb）。
