Zheng Guoyang, Li Hanzhong, Li Ji, Zhang Xuebin, Zhang Yushi, Wu Xingcheng
Department of Urology Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Medicine (Baltimore). 2017 Jan;96(1):e5720. doi: 10.1097/MD.0000000000005720.
Renal cell carcinoma metastasizing to rectum is very rare, and the unusual metastatic sites should be paid attention to during the follow-up of renal cell carcinoma.
We describe a case of a 65-year-old male who was diagnosed with metastatic renal cell carcinoma to rectum 10 years after the right radical nephrectomy. Histopathology and immunohistochemical examinations contribute to making differential diagnosis between rectal metastasis of renal cell carcinoma and primary rectal clear cell carcinoma. Positron emission tomography-computed tomography with fluorodeoxyglucose shows hypermetabolic activity in upper rectum and other sites of metastasis at the same time.
Possibility of unusual metastatic sites of renal cell carcinoma such as rectum indeed exists, which should not be ignored in the surveillance after resection of the primary tumor.
肾细胞癌转移至直肠非常罕见,在肾细胞癌的随访过程中应注意这些不寻常的转移部位。
我们描述了一例65岁男性患者,在右肾根治性切除术后10年被诊断为肾细胞癌转移至直肠。组织病理学和免疫组化检查有助于鉴别肾细胞癌直肠转移和原发性直肠透明细胞癌。氟脱氧葡萄糖正电子发射断层扫描计算机断层扫描显示直肠上段及其他转移部位同时存在高代谢活性。
肾细胞癌转移至直肠等不寻常部位的可能性确实存在,在原发肿瘤切除后的监测中不应忽视。