McMillan A, Bishop P E
Genitourinary Medicine Unit, Royal Infirmary, Edinburgh.
Genitourin Med. 1989 Aug;65(4):225-8. doi: 10.1136/sti.65.4.225.
Fifty four men with anogenital warts were studied; 22 had concurrent infection with the human immunodeficiency virus (HIV). The median duration of the warts before and after the start of treatment of seven HIV infected and 10 non-infected heterosexual men was similar. In homosexual men, however, the duration of the lesions in 15 HIV infected patients was greater before and after treatment than in 22 non-HIV infected men. As the median number of CD4+ cells in the peripheral blood was significantly lower in homosexual than heterosexual men infected with HIV, the difference in the course of anogenital warts in homosexual compared with heterosexual men may reflect different degrees of immunosuppression.
对54名患有肛门生殖器疣的男性进行了研究；其中22人同时感染了人类免疫缺陷病毒（HIV）。7名感染HIV的异性恋男性和10名未感染HIV的异性恋男性在开始治疗前后，疣的持续时间中位数相似。然而，在同性恋男性中，15名感染HIV的患者在治疗前后病变的持续时间比22名未感染HIV的男性更长。由于感染HIV的同性恋男性外周血中CD4+细胞的中位数明显低于异性恋男性，因此与异性恋男性相比，同性恋男性肛门生殖器疣病程的差异可能反映了不同程度的免疫抑制。
