Zhong Ming, Liu Jin-Tao, Jiang Hong, Mo Wen, Yu Peng-Fei, Li Xiao-Chun, Xue Rui Rui
Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Department of Orthopaedic Surgery, Suzhou Hospital of Traditional Chinese Medicine, Jiangsu, China.
Department of Orthopaedic Surgery, Suzhou Hospital of Traditional Chinese Medicine, Jiangsu, China.
Pain Physician. 2017 Jan-Feb;20(1):E45-E52.
Lumbar disc herniation (LDH), a common disease, is often treated conservatively, frequently resulting in spontaneous resorption of the herniated disc. The incidence of this phenomenon, however, remains unknown.
To analyze the incidence of spontaneous resorption after conservative treatment of LDH using computed tomography and magnetic resonance imaging.
Meta-analysis and systematic review of cohort studies.
The work was performed at The Suzhou Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine.
We initiated a search for the period from January 1990 to December 2015 using PubMed, Embase, and the Cochrane Library. Two independent reviewers examined the relevant reports. The references from these reports were also searched for additional trials using the criteria established in the PRISMA statement.
Our results represent the pooled results from 11 cohort studies. The overall incidence of spontaneous resorption after LDH was 66.66% (95% CI 51% - 69%). The incidence in the United Kingdom was 82.94% (95% CI 63.77% - 102.11%). The incidence in Japan was 62.58% (95% CI 55.71% - 69.46%).
Our study was limited because there were few sources from which to extract data, either in abstracts or published studies. There were no randomized, controlled trials that met our criteria.
The phenomenon of LDH reabsorption is well recognized. Because its overall incidence is now 66.66% according to our results, conservative treatment may become the first choice of treatment for LDH. More large-scale, double-blinded, randomized, controlled trials are necessary to study the phenomenon of spontaneous resorption of LDH.Key words: Lumbar, disc herniation, spontaneous resorption, conservative treatment, incidence, country, meta-analysis, systematic review, observational studies, study designs.
腰椎间盘突出症（LDH）是一种常见疾病，通常采用保守治疗，常常会导致突出的椎间盘自发吸收。然而，这种现象的发生率仍然未知。
使用计算机断层扫描和磁共振成像分析LDH保守治疗后自发吸收的发生率。
队列研究的荟萃分析和系统评价。
该研究在上海中医药大学附属苏州市中医医院开展。
我们使用PubMed、Embase和Cochrane图书馆进行了1990年1月至2015年12月期间的检索。两名独立的评审员检查了相关报告。还根据PRISMA声明中确立的标准，对这些报告的参考文献进行检索以寻找其他试验。
我们的结果代表了11项队列研究的汇总结果。LDH后自发吸收的总体发生率为66.66%（95%CI 51% - 69%）。英国的发生率为82.94%（95%CI 63.77% - 102.11%）。日本的发生率为62.58%（95%CI 55.71% - 69.46%）。
我们的研究受到限制，因为无论是摘要还是已发表的研究，可供提取数据的来源都很少。没有符合我们标准的随机对照试验。
LDH再吸收现象已得到充分认识。根据我们的结果，由于其总体发生率现在为66.66%，保守治疗可能成为LDH的首选治疗方法。需要更多大规模、双盲、随机对照试验来研究LDH自发吸收现象。关键词：腰椎，椎间盘突出症，自发吸收，保守治疗，发生率，国家，荟萃分析，系统评价，观察性研究，研究设计
