Neurobiology Section, Department of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0357, USA.
Curr Biol. 2017 Jan 9;27(1):R38-R41. doi: 10.1016/j.cub.2016.11.031.
How Drosophila larvae select one behavior or a sequence of behaviors, and then persist in the final one, has been addressed by a powerful combination of electron-microscopy reconstruction of neuronal connections, genetic manipulations, electrophysiology, and neuronal modeling. Surprisingly, reciprocal inhibitory synaptic connections are major players in choosing, sequencing and maintaining behaviors.
果蝇幼虫如何选择一种行为或一系列行为,然后坚持最终的行为,这一问题已通过电子显微镜重建神经元连接、遗传操作、电生理学和神经元建模的强大组合得到解决。令人惊讶的是,相互抑制性突触连接是选择、排序和维持行为的主要参与者。