Oraie Mehdi, Hosseini Mir-Jamal, Islambulchilar Mina, Hosseini Seyed-Hasan, Ahadi-Barzoki Mehdi, Sadr Habib, Yaghoubi Hashem
Clinical Laboratory Science, Azad University of Medical Sciences, Tabriz, Iran.
Department of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Drug Res (Stuttg). 2017 Mar;67(3):183-188. doi: 10.1055/s-0042-122007. Epub 2017 Jan 10.
Chemical substances have an important threat due to extensive use in medicine, agriculture, industry and environment. In this retrospective study, etiological and demographic characteristics of acute poisoning cases admitted to a hospital in Iran were investigated. We compared these data with those reported from other parts of the country and the international experiences to evaluate any difference if exists. 7 052 poisoned cases admitted to the hospital from April 2006 to March 2013, by data collected from the medical record in poison center section. According to our results there is a predominance of male patients and the majority of the poisoned patients were between 20-30 years old. Drug poisoning was the most common cause of poisonings. The most frequently involved drugs were benzodiazepines and antidepressants. The seasonal distribution of our study showed a peak in summer. To prevent acute poisonings, the social education about the risk assessment of central nervous system-acting drugs and reduction of the exposure period of people to pesticides are recommended. This study suggested a proper educational program for the public and primary care units. Our results provide useful information for preventive strategies.
由于化学物质在医学、农业、工业和环境中的广泛使用，它们构成了重大威胁。在这项回顾性研究中，我们调查了伊朗一家医院收治的急性中毒病例的病因和人口统计学特征。我们将这些数据与该国其他地区报告的数据以及国际经验进行了比较，以评估是否存在差异。通过收集中毒中心科室病历中的数据，我们获取了2006年4月至2013年3月期间收治到该医院的7052例中毒病例。根据我们的研究结果，男性患者居多，大多数中毒患者年龄在20至30岁之间。药物中毒是最常见的中毒原因。最常涉及的药物是苯二氮䓬类药物和抗抑郁药。我们研究的季节分布显示夏季为高峰期。为预防急性中毒，建议开展关于中枢神经系统作用药物风险评估的社会教育，并减少人们接触农药的时间。这项研究为公众和基层医疗单位提出了一个适当的教育计划。我们的研究结果为预防策略提供了有用信息。
