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对急诊医学收治的中毒病例进行回顾性分析。

Retrospective analysis of poisoning cases admitted to the emergency medicine.

作者信息

Zöhre Erhan, Ayrık Cüneyt, Bozkurt Seyran, Köse Ataman, Narcı Hüseyin, Çevik İbrahim, Toker İbrahim, Demir Filiz, Ovla Didem

机构信息

Tarsus State Hospi̇tal Department of Emergency Medi̇ci̇ne, Mersin, Turkey.

Mersin University Medical Faculty, Emergency Medicine Department, Mersin, Turkey.

出版信息

Arch Iran Med. 2015 Feb;18(2):117-22.

Abstract

BACKGROUND

We aimed herein to assess demographic, etiological, and clinical characteristics of patients presenting to our hospital's emergency department with acute poisoning.

METHOD

This study included a total of 509 (0.27%) patients diagnosed with poisoning at our emergency department within a 3-year period. This was a retrospective study.

RESULTS

Seventy-one point three (n = 363) percent of the patients were female. The majority of the victims were in the 18-25 years age group (P < 0.001). The poisoning incident was for suicidal purposes in 83.7% of patients. Among the patients presenting with prescription drug poisoning, 92.9% were poisoned in a suicide attempt while 73.2% of patients presenting with poisoning with non-medical substances were poisoned accidentally. Suicidal poisonings were more common in young age group and females (P < 0.001). The most common poisoning agent was antidepressants (17.6%) followed by analgesics (12.8%), and other psychotropic drugs (6.1%). Antidepressant drugs were the most common prescription drugs taken for suicidal purposes (P < 0.001). Poisonings occurred with a single agent in 72.5% of cases and with two or more agents in 27.5% of cases.  Analysis of duration of hospital stay revealed that 52.6% (n = 60) of patients stayed in hospital for 2 days. The mortality rate was 0.4%.

CONCLUSION

The majority of poisonings were with prescription drugs, for suicidal purposes, in young age group, and in females. In our study, the three most common agents causing poisoning were antidepressants, analgesics, and other psychotropic substances.

摘要

背景

我们旨在评估我院急诊科收治的急性中毒患者的人口统计学、病因学和临床特征。

方法

本研究纳入了3年内我院急诊科诊断为中毒的509例(0.27%)患者。这是一项回顾性研究。

结果

71.3%(n = 363)的患者为女性。大多数受害者年龄在18 - 25岁组(P < 0.001)。83.7%的患者中毒事件是出于自杀目的。在出现处方药中毒的患者中,92.9%是在自杀企图中中毒,而出现非医疗物质中毒的患者中73.2%是意外中毒。自杀性中毒在年轻年龄组和女性中更为常见(P < 0.001)。最常见的中毒药物是抗抑郁药(17.6%),其次是镇痛药(12.8%)和其他精神药物(6.1%)。抗抑郁药是自杀目的服用最常见的处方药(P < 0.001)。72.5%的病例中毒由单一药物引起,27.5%的病例由两种或更多药物引起。住院时间分析显示,52.6%(n = 60)的患者住院2天。死亡率为0.4%。

结论

大多数中毒是由处方药引起,出于自杀目的,发生在年轻年龄组和女性中。在我们的研究中,引起中毒的三种最常见药物是抗抑郁药、镇痛药和其他精神药物。

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