Vella Ivan, di Francesco Fabrizio, Accardo Caterina, Boggi Ugo, Gruttadauria Salvatore
Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (IRCCS-ISMETT), University of Pittsburgh Medical Center (UPMC), Via E. Tricomi 5, 90127, Palermo, Italy.
Division of General and Transplant Surgery, University of Pisa, Pisa, Italy.
Updates Surg. 2024 May 27. doi: 10.1007/s13304-024-01785-8.
The shortage of deceased liver donor organs over the years has always posed the need to expand the donor pool. A viable alternative to deceased donors is that of the living donor. Indeed, the living donor in liver transplantation, initially in pediatric transplantation, but for several years now also in adult transplantation, is a more than viable alternative to deceased liver donation. In fact, right liver lobe donation has proven to be a surgical procedure with low impact on the donor's life in terms of morbidity and mortality, with excellent results in recipients of such organs. In recent years, an increasing number of studies have been published that show excellent results in right-lobe living donor liver transplantation, encouraging this practice not only in countries that have historically had a shortage of deceased donor organs, such as Asian countries, but making it a practice of increasing use in Western countries as well. In addition, thanks to improvements in surgical technique and the experience of high-volume centers, this surgery has also begun to be performed using minimally invasive surgical techniques, allowing us to envision ever better outcomes for both donor and recipient in the coming years.
多年来，已故肝脏供体器官的短缺一直表明有必要扩大供体库。活体供体是已故供体的一个可行替代方案。事实上，肝脏移植中的活体供体，最初用于小儿移植，但如今多年来也用于成人移植，是已故肝脏捐赠的一个非常可行的替代方案。实际上，右肝叶捐赠已被证明是一种对供体生活在发病率和死亡率方面影响较小的外科手术，在接受此类器官的受者中取得了优异的效果。近年来，越来越多的研究表明右叶活体供体肝移植取得了优异的成果，这不仅鼓励了在历史上已故供体器官短缺的国家（如亚洲国家）开展这种做法，也使其在西方国家的使用越来越多。此外，由于外科技术的改进和大容量中心的经验，这种手术也开始采用微创手术技术进行，使我们能够预见在未来几年供体和受者都能取得更好的结果。
