Tonstad Serena
Seksjon for preventiv kardiologi Avdeling for endokrinologi, sykelig overvekt og forebyggende medisin Oslo universitetssykehus.
Tidsskr Nor Laegeforen. 2017 Jan 10;137(1):36-38. doi: 10.4045/tidsskr.16.0646. eCollection 2017 Jan.
In 2015, more than 530 000 people were prescribed statins in Norway. Adverse effects from the musculoskeletal system as well as less specific side effects are frequently reported. The extent of these contrasts with observations made in randomised controlled studies which report the prevalence of such adverse effects as being in line with placebo. Breaks from drug treatment, low doses, switching medication and use of other lipid-lowering drugs are the most relevant approaches to dealing with adverse effects.
2015年,挪威有超过53万人被开具了他汀类药物的处方。肌肉骨骼系统的不良反应以及不太明确的副作用屡有报告。这些不良反应的程度与随机对照研究中的观察结果形成对比,后者报告此类不良反应的发生率与安慰剂一致。中断药物治疗、低剂量用药、更换药物以及使用其他降脂药物是应对不良反应最相关的方法。