Friedman Joseph H
Butler Hospital, Dept of Neurology, Warren Alpert Medical School of Brown University, 345 Blackstone Blvd, Providence, RI 02906, USA.
J Neurol Sci. 2017 Mar 15;374:42-46. doi: 10.1016/j.jns.2016.12.059. Epub 2017 Jan 4.
Most of the neurobehavioral aspects of Parkinson's disease have been well established and studied, but many are not well known, and hardly studied. This article focuses on several behavioral abnormalities that are common, and frequently cause difficulty for the patient and family due to lack of recognition as part of the disease. While it is well known that L-Dopa dyskinesias are frequently not recognized or under appreciated by patients, a similar lack of recognition may affect the patient's own speech volume, where their center of gravity is located, whether they are tilted to one side, and their under-recognition of others' emotional displays. In addition, PD patients are often misperceived by others incorrect impression of their emotional and cognitive state based purely on facial expression. These changes and others are briefly reviewed.
帕金森病的大多数神经行为方面已经得到充分证实和研究,但也有许多并不为人熟知,且几乎未被研究。本文聚焦于几种常见的行为异常,由于未被视为该疾病的一部分而常常不被认识,这给患者及其家人带来诸多困扰。众所周知,左旋多巴引起的运动障碍常常未被患者认识或重视,类似地,对自身说话音量、重心位置、是否向一侧倾斜以及对他人情绪表露的认识不足等情况也可能影响患者。此外,仅基于面部表情,他人常常会对帕金森病患者的情绪和认知状态产生错误的感知。本文将简要回顾这些变化及其他情况。