蓝藻有毒特化代谢物的遗传学、生物合成和调控。
The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria.
机构信息
Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney 2052, NSW, Australia.
Institut für Biochemie und Biologie, Mikrobiologie, Universität Potsdam, Potsdam-Golm 14476, Germany.
出版信息
Harmful Algae. 2016 Apr;54:98-111. doi: 10.1016/j.hal.2015.11.002.
The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the microcystins, nodularin, cylindrospermopsin, saxitoxins and anatoxins, as well as the lesser-known marine toxins (e.g. lyngbyatoxin, aplysiatoxin, jamaicamides, barbamide, curacin, hectochlorin and apratoxins).
蓝藻水华产生的有毒代谢物对全世界人类和生态系统的健康构成了重大威胁。在这里，我们总结了目前关于特征明确的蓝藻毒素（包括微囊藻毒素、节球藻毒素、柱孢藻毒素、石房蛤毒素和anatoxins）的遗传学、生物合成和调控的知识现状，以及不太为人知的海洋毒素（例如，lyngbyatoxin、aplysiatoxin、jamaicamides、barbamide、curacin、hectochlorin 和 apratoxins）。
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