Depaoli M A, Bedello P G, Tamponi M
G Ital Dermatol Venereol. 1989 Mar;124(3):71-2.
Azidothymidine is a new antiviral drug that acts by competitive inhibition of reverse transcriptase of retroviruses. Azidothymidine is now widely used in treatment of patients with AIDS or ARC; the most important side effects of this drug are anaemia and neutropenia. Recently pigmentary changes of the nails (diffuse pigmentation and longitudinal or transverse bands) provoked by azidothymidine-treatment have also been reported. We describe a such case.
叠氮胸苷是一种新型抗病毒药物，其作用机制是竞争性抑制逆转录病毒的逆转录酶。叠氮胸苷目前广泛用于治疗艾滋病或艾滋病相关综合征患者；该药物最重要的副作用是贫血和中性粒细胞减少。最近也有报道称，叠氮胸苷治疗会引发指甲色素沉着改变（弥漫性色素沉着以及纵向或横向条纹）。我们描述了这样一个病例。
