Campos Adriana Gondim de Moura, Lira Rodrigo Pessoa Cavalcanti, Arantes Tiago Eugenio Faria E
Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
Arq Bras Oftalmol. 2016 Nov-Dec;79(6):400-401. doi: 10.5935/0004-2749.20160112.
This case report describes the retinal optical coherence tomography (OCT) findings in a microcephalic infant with macular atrophy presumably caused by intrauterine Zika virus infection. OCT demonstrated atrophy of the outer retinal layers and choriocapillaris, including the outer nuclear layer and ellipsoid zone, associated with retinal pigment epithelium hyper-reflectivity and increased OCT penetration into deeper layers of the choroid and sclera. A major concern associated with this infection is the apparent increased incidence of microcephaly in fetuses born to mothers infected with the Zika virus. It is becoming increasingly difficult to ignore the upsurge in congenital microcephaly observed in Brazil. Recently, ocular findings in infants with microcephaly associated with intrauterine Zika virus infection have been described. This is the first report of OCT imaging of macular atrophy in a child with presumed Zika virus infection-associated microcephaly.
本病例报告描述了一名小头畸形婴儿的视网膜光学相干断层扫描（OCT）检查结果，该婴儿的黄斑萎缩可能由子宫内寨卡病毒感染所致。OCT显示视网膜外层和脉络膜毛细血管萎缩，包括外核层和椭圆体带，伴有视网膜色素上皮高反射性以及OCT对脉络膜和巩膜深层的穿透增加。与这种感染相关的一个主要担忧是，感染寨卡病毒的母亲所生胎儿小头畸形的发病率明显增加。巴西观察到的先天性小头畸形激增现象已越来越难以忽视。最近，已有关于子宫内寨卡病毒感染相关小头畸形婴儿眼部检查结果的描述。这是首例关于疑似寨卡病毒感染相关小头畸形患儿黄斑萎缩的OCT成像报告。
