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芬兰缺血性心脏病死亡率的趋势及决定因素:特别提及20世纪80年代初可能出现的趋于平稳态势。

Trends and determinants of ischaemic heart disease mortality in Finland: with special reference to a possible levelling off in the early 1980s.

作者信息

Tuomilehto J, Puska P, Korhonen H, Mustaniemi H, Vartiainen E, Nissinen A, Kuulasmaa K, Niemensivu H, Salonen J T

机构信息

Department of Epidemiology, National Health Institute Mannerheimintic Helsinki, Finland.

出版信息

Int J Epidemiol. 1989;18(3 Suppl 1):S109-17.

PMID:2807690
Abstract

There has been a general decline in mortality from ischaemic heart disease (IHD) in Finland since the beginning of the 1970s. An intensified preventive programme was started in the province of North Karelia in 1972. Between 1974 and 1979 the decline in IHD mortality in North Karelian men was steeper than that in the rest of Finland. This favourable trend was associated with a fall in the levels of major coronary disease risk factors. Case-fatality from acute coronary events did not change much during this period. A levelling off in the decline in IHD mortality has been observed in the 1980s first in North Karelia and later in the whole of Finland. These findings from the official mortality statistics were confirmed in North Karelia by the data from the population-based coronary register. This levelling off in the decline in IHD mortality was associated with levelling off in risk-factor reductions in eastern Finland and with little improvement in risk-related behaviours in Finland during the 1980s. The IHD rates are still high and associated with persistent high risk factor levels and particularly with high serum cholesterol and blood pressure levels. Together with IHD mortality, the decline in total mortality also levelled off both in North Karelia and in the rest of Finland during the early 1980s. Compared with other countries, the rates of coronary disease and total mortality in the middle-aged Finnish population, especially among men, are among the highest in the world.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

自20世纪70年代初以来,芬兰缺血性心脏病(IHD)的死亡率总体呈下降趋势。1972年,北卡累利阿省启动了一项强化预防计划。1974年至1979年间,北卡累利阿男性IHD死亡率的下降幅度比芬兰其他地区更大。这一有利趋势与主要冠心病危险因素水平的下降有关。在此期间,急性冠状动脉事件的病死率变化不大。20世纪80年代,首先在北卡累利阿,随后在整个芬兰,IHD死亡率下降趋势趋于平稳。基于人群的冠心病登记数据在北卡累利阿证实了官方死亡率统计的这些结果。IHD死亡率下降趋势的平稳与芬兰东部危险因素降低的平稳以及20世纪80年代芬兰与风险相关行为改善甚微有关。IHD发病率仍然很高,与持续的高危险因素水平相关,尤其是高血清胆固醇和血压水平。20世纪80年代初,北卡累利阿和芬兰其他地区的总死亡率下降趋势也趋于平稳。与其他国家相比,芬兰中年人群,尤其是男性的冠心病发病率和总死亡率在世界上名列前茅。(摘要截选至250字)

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