Rambaud-Althaus Clotilde, Shao Amani, Samaka Josephine, Swai Ndeniria, Perri Seneca, Kahama-Maro Judith, Mitchell Marc, D'Acremont Valérie, Genton Blaise
Swiss Tropical and Public Health Institute, Basel, Switzerland.
University of Basel, Basel, Switzerland.
Am J Trop Med Hyg. 2017 Jan 11;96(1):249-257. doi: 10.4269/ajtmh.15-0395. Epub 2016 Nov 14.
In low-resource settings, where qualified health workers (HWs) are scarce and childhood mortality high, rational antimicrobial prescription for childhood illnesses is a challenge. To assess whether smartphones running guidelines, as compared with paper support, improve consultation process and rational use of medicines for children, a pilot cluster-randomized controlled study was conducted in Tanzania. Nine primary health-care facilities (HFs) were randomized into three arms: 1) paper algorithm, 2) electronic algorithm on a smartphone, and 3) control. All HWs attending children aged 2-59 months for acute illness in intervention HFs were trained on a new clinical algorithm for management of childhood illness (ALMANACH) either on 1) paper or 2) electronic support; 4 months after training, consultations were observed. An expert consultation was the reference for classification and treatment. Main outcomes were proportion of children checked for danger signs, and antibiotics prescription rate. A total of 504 consultations (166, 171, and 167 in control, paper, and phone arms, respectively) were observed. The use of smartphones versus paper was associated with a significant increase in children checked for danger signs (41% versus 74%, P = 0.04). Antibiotic prescriptions rate dropped from 70% in the control to 26%, and 25% in paper and electronic arms. The HWs-expert agreement on pneumonia classification remained low (expert's pneumonia identified by HWs in 26%, 30%, and 39% of patients, respectively).Mobile technology in low-income countries is implementable and has a potential to improve HWs' performance. Additional point-of-care diagnostic tests are needed to ensure appropriate management. Improving the rational use of antimicrobial is a challenge that ALMANACH can help to take up.
在资源匮乏地区,合格的卫生工作者稀缺且儿童死亡率高,为儿童疾病合理开具抗菌药物处方是一项挑战。为评估运行指南的智能手机与纸质辅助工具相比,是否能改善儿童疾病的诊疗过程及药物合理使用情况,在坦桑尼亚开展了一项群组随机对照试验。9家初级卫生保健机构被随机分为三组:1)纸质算法组,2)智能手机电子算法组,3)对照组。所有在干预性卫生保健机构中为2至59个月大的急性病患儿看病的卫生工作者,均接受了关于儿童疾病管理新临床算法(ALMANACH)的培训,培训方式为1)纸质或2)电子辅助;培训4个月后,观察诊疗情况。专家会诊作为分类和治疗的参考。主要结果是检查危险体征的儿童比例和抗生素处方率。共观察了504次诊疗(对照组、纸质组和手机组分别为166、171和167次)。与纸质工具相比,使用智能手机显著增加了检查危险体征的儿童比例(41%对74%,P = 0.04)。抗生素处方率从对照组的70%降至纸质组和电子组的26%和25%。卫生工作者与专家在肺炎分类上的一致性仍然较低(卫生工作者分别在26%、30%和39%的患者中识别出专家认定的肺炎)。低收入国家的移动技术是可行的,并且有改善卫生工作者表现的潜力。需要额外的即时诊断检测来确保恰当的管理。改善抗菌药物的合理使用是一项挑战,而ALMANACH有助于应对这一挑战。