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在使用5-氨基水杨酸的情况下,转移性胃癌至结肠的影像学及内镜下消退情况

Radiographic and endoscopic regression of metastatic gastric cancer to the colon in the setting of 5-aminosalicylic acid use.

作者信息

Patel Yuval A, McCall Shannon J, Zhang Xuefeng, Jaffe Tracy, Shimpi Rahul A

机构信息

Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.

Department of Pathology, Duke University Medical Center, Durham, NC, USA.

出版信息

J Gastrointest Oncol. 2016 Dec;7(6):E88-E92. doi: 10.21037/jgo.2016.05.02.

DOI:10.21037/jgo.2016.05.02
PMID:28078130
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5177585/
Abstract

Colonic metastases from gastric cancer are a rare phenomenon and sparsely reported in the literature. We report a case of a 59-year-old woman who presented with vague abdominal symptoms and initial computer tomography (CT) imaging suggestive of a colonic apple-core lesion with serial colonoscopic biopsies diagnostic of metastatic signet ring cell gastric adenocarcinoma. This case is unique given the evolving CT and endoscopic findings that suggested a regression in colonic wall thickening in the setting of 5-aminosalicylic acid (5-ASA) use prior to histologic diagnosis.

摘要

胃癌的结肠转移是一种罕见现象,文献报道较少。我们报告一例59岁女性,她出现模糊的腹部症状,最初的计算机断层扫描(CT)成像提示结肠苹果核样病变,经系列结肠镜活检诊断为转移性印戒细胞胃腺癌。鉴于在组织学诊断之前使用5-氨基水杨酸(5-ASA)时,CT和内镜检查结果不断变化,提示结肠壁增厚有所消退,该病例具有独特性。

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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.全球癌症发病与死亡:GLOBOCAN 2012 数据源、方法与主要模式。
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Stage-stratified prognosis of signet ring cell histology in patients undergoing curative resection for gastric adenocarcinoma.接受胃癌根治性切除术患者中印戒细胞组织学的分期分层预后
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Prognostic significance of signet ring gastric cancer.印戒细胞胃癌的预后意义。
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Metachronous Colon Metastases from Gastric Adenocarcinoma: A Case Report.胃腺癌的异时性结肠转移:一例报告
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Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.5-氨基水杨酸对结肠癌细胞增殖的环氧化酶-2依赖性和非依赖性抑制作用
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