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一种具有聚集诱导发光（AIE）特性的抗菌肽，可用于研究细菌膜相互作用和抗菌作用。

An antimicrobial peptide with an aggregation-induced emission (AIE) luminogen for studying bacterial membrane interactions and antibacterial actions.

机构信息

Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing, 400715, China.

Department of Chemical & Biomolecular Engineering, National University of Singapore, 117576, Singapore.

出版信息

Chem Commun (Camb). 2017 Mar 16;53(23):3315-3318. doi: 10.1039/c6cc09408b.

DOI:10.1039/c6cc09408b
PMID:28078346
Abstract

A fluorescence technique to investigate the interactions between bacterial membranes and an aggregation-induced emission (AIE) luminogen-decorated AMP (TPE-AMP) was reported. Our simple and fast method consists of mixing TPE-AMP and bacterial suspensions and recording the fluorescence signals by flow cytometry and confocal microscopy in a "non-washing" manner.

摘要

本文报道了一种荧光技术，用于研究细菌膜与聚集诱导发光（AIE）发光体修饰的 AMP（TPE-AMP）之间的相互作用。我们的简单快速方法包括将 TPE-AMP 与细菌悬浮液混合，并通过流式细胞术和共聚焦显微镜以“非洗涤”方式记录荧光信号。

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